دورية أكاديمية
أعرض في EDS

Trends in the use of immunosuppressive agents by outpatients after renal transplantation at a medical center in southern Taiwan.

التفاصيل البيبلوغرافية
العنوان: Trends in the use of immunosuppressive agents by outpatients after renal transplantation at a medical center in southern Taiwan.
المؤلفون: Mao PC; Clinical Pharmacy Division, Department of Pharmacy, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan., Lee EK, Tseng PL
المصدر: Transplantation proceedings [Transplant Proc] 2012 Jan; Vol. 44 (1), pp. 185-9.
نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't
اللغة: English
بيانات الدورية: Publisher: Elsevier Science Inc Country of Publication: United States NLM ID: 0243532 Publication Model: Print Cited Medium: Internet ISSN: 1873-2623 (Electronic) Linking ISSN: 00411345 NLM ISO Abbreviation: Transplant Proc Subsets: MEDLINE
أسماء مطبوعة: Publication: New York, N.Y. : Elsevier Science Inc.
Original Publication: New York Stratton.
مواضيع طبية MeSH: Kidney Transplantation*/economics , Kidney Transplantation*/immunology, Ambulatory Care/*trends , Graft Rejection/*prevention & control , Immunosuppression Therapy/*trends , Immunosuppressive Agents/*therapeutic use , Practice Patterns, Physicians'/*trends, Adult ; Azathioprine/therapeutic use ; Cyclosporine/therapeutic use ; Drug Costs/trends ; Drug Therapy, Combination ; Drug Utilization/trends ; Graft Rejection/immunology ; Graft Survival/drug effects ; Humans ; Immunosuppression Therapy/adverse effects ; Immunosuppression Therapy/economics ; Immunosuppressive Agents/adverse effects ; Immunosuppressive Agents/economics ; Mycophenolic Acid/analogs & derivatives ; Mycophenolic Acid/therapeutic use ; Practice Patterns, Physicians'/economics ; Prednisolone/therapeutic use ; Sirolimus/therapeutic use ; Tacrolimus/therapeutic use ; Taiwan ; Time Factors ; Treatment Outcome
مستخلص: Kidney transplantation has become an effective treatment for end-stage renal failure. This study analyzed trends in immunosuppressive agent use after renal transplantation at a medical center in southern Taiwan over a 9-year period (2000-2008) seeking to determine whether the trends were consistent with clinical trial outcomes and published guidelines. We identified adult outpatients who had diagnoses of renal transplantation and who had concurrent immunosuppressive drug claims. From 2000-2008, we discovered 39,189 prescriptions related to kidney transplantation. The overall medication consumption showed an increase from 4.9% to 31.9%. Cyclosporine was the main determinant of overall drug costs during these 9 years. The long-term prescribing trend for immunosuppressive use among renal transplantation outpatients showed a clear change during the course of the study. Tacrolimus and sodium mycophenolate/mycophenolate mofetil were used increasingly as combination therapy. However, our survey revealed that management of this transplantation population, especially regarding the use of either calcineurin inhibitor or corticosteroids, was based on potential long-term side effects.
(Copyright © 2012 Elsevier Inc. All rights reserved.)
المشرفين على المادة: 0 (Immunosuppressive Agents)
83HN0GTJ6D (Cyclosporine)
9PHQ9Y1OLM (Prednisolone)
HU9DX48N0T (Mycophenolic Acid)
MRK240IY2L (Azathioprine)
W36ZG6FT64 (Sirolimus)
WM0HAQ4WNM (Tacrolimus)
تواريخ الأحداث: Date Created: 20120208 Date Completed: 20120524 Latest Revision: 20211203
رمز التحديث: 20231215
DOI: 10.1016/j.transproceed.2011.11.003
PMID: 22310611
قاعدة البيانات: MEDLINE
الوصف
تدمد:1873-2623
DOI:10.1016/j.transproceed.2011.11.003