دورية أكاديمية
Double-blind randomized controlled trial of rolls fortified with microencapsulated iron.
| العنوان: | Double-blind randomized controlled trial of rolls fortified with microencapsulated iron. |
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| المؤلفون: | Barbosa TN; Department of Pediatrics, Universidade de Santo Amaro, São Paulo, Brazil. teresanb@globo.com, Taddei JA, Palma D, Ancona-Lopez F, Braga JA |
| المصدر: | Revista da Associacao Medica Brasileira (1992) [Rev Assoc Med Bras (1992)] 2012 Jan-Feb; Vol. 58 (1), pp. 118-24. |
| نوع المنشور: | Journal Article; Randomized Controlled Trial |
| اللغة: | English |
| بيانات الدورية: | Publisher: Associação Médica Brasileira Country of Publication: Brazil NLM ID: 9308586 Publication Model: Print Cited Medium: Internet ISSN: 1806-9282 (Electronic) Linking ISSN: 01044230 NLM ISO Abbreviation: Rev Assoc Med Bras (1992) Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: São Paulo : Associação Médica Brasileira |
| مواضيع طبية MeSH: | Bread* , Food, Fortified*, Anemia, Iron-Deficiency/*prevention & control , Ferrous Compounds/*administration & dosage , Hemoglobin A/*analysis , Iron, Dietary/*administration & dosage, Anemia, Iron-Deficiency/blood ; Anemia, Iron-Deficiency/diet therapy ; Brazil ; Child ; Child, Preschool ; Double-Blind Method ; Drug Compounding ; Hemoglobin A/metabolism ; Humans ; Nutritional Status |
| مستخلص: | Objective: To evaluate the impact of the fortification of rolls with microencapsulated iron sulfate with sodium alginate on the hemoglobin levels in preschoolers as compared to controls. Methods: Double-blind randomized controlled trial comprised of children aged 2 to 6 years with initial hemoglobin exceeding 9 g/dL from four not-for-profit daycares randomly selected in the city of São Paulo - Brazil. Children of 2 daycares (n = 88) received rolls with fortified wheat flour as the exposed group (EC) and children of 2 daycares (n = 85) received rolls without fortification as the control group (CG) over a 24-week period. Rolls with 4 mg iron each were offered once a day, five days a week. Hemoglobin concentrations were determined in capillary blood by HemoCue® at three moments of trial: baseline (Ml), after 12 and 24 weeks of intervention (M2, M3). Results: Hemoglobin concentration presented significant increase up to M3 in EG (11.7-12.5-12.6 g/dL) and in CG (11.1-12.4-12.3 g/dL) with higher elevations in children initially with anemia. There was significant reduction in the occurrence of anemia from 22% to 9% in EG and from 47% to 8.2% in CG at M3. Conclusion: Rolls fortified with microencapsulated iron sulfate were well tolerated, increased hemoglobin levels and reduced the occurrence of anemia, but with no difference compared to the control group. |
| المشرفين على المادة: | 0 (Ferrous Compounds) 0 (Iron, Dietary) 9034-51-9 (Hemoglobin A) |
| تواريخ الأحداث: | Date Created: 20120307 Date Completed: 20120713 Latest Revision: 20160815 |
| رمز التحديث: | 20240628 |
| PMID: | 22392326 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 1806-9282 |
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