دورية أكاديمية
Passive smoke exposure of female rats caused aortic atherosclerotic precursor lesions in their offspring.
| العنوان: | Passive smoke exposure of female rats caused aortic atherosclerotic precursor lesions in their offspring. |
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| المؤلفون: | Tunc T; Gulhane Military Medical Academy, Etlik, Turkey., Sarici U, Aydinoz S, Onguru O, Karaoglu A, Uysal B, Kul M, Sirin YS, Oztas E, Yaman H |
| المصدر: | Fetal and pediatric pathology [Fetal Pediatr Pathol] 2012 Jun; Vol. 31 (3), pp. 120-7. Date of Electronic Publication: 2012 Mar 13. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Informa Healthcare Country of Publication: England NLM ID: 101230972 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1551-3823 (Electronic) Linking ISSN: 15513815 NLM ISO Abbreviation: Fetal Pediatr Pathol Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: London : Informa Healthcare Original Publication: Philadelphia, PA : Taylor & Francis, c2004- |
| مواضيع طبية MeSH: | Aorta, Abdominal/*pathology , Coronary Artery Disease/*etiology , Coronary Artery Disease/*pathology , Prenatal Exposure Delayed Effects/*pathology , Tobacco Smoke Pollution/*adverse effects, Animals ; Female ; Pregnancy ; Rats ; Rats, Wistar |
| مستخلص: | The aim of this study was to evaluate the presence and degree of preclinical atherosclerosis in pups of pregnant rats exposed to cigarette smoke. Abdominal aorta examined for atherosclerotic lesions and intimal medial thickness of the abdominal aorta was measured by image analysis. The study groups showed endothelial cellular losses, marked intimal injuries, elastic fiber damages, mononuclear cellular infiltration, and irregularities in internal elastic membrane, with pronounced damages as integrity losses and local fragmentations. The results provide evidence for development of an atherosclerotic process in the neonatal period, even in prenatal stage, long before the formation of smoke-related cardiovascular diseases. |
| المشرفين على المادة: | 0 (Tobacco Smoke Pollution) |
| تواريخ الأحداث: | Date Created: 20120315 Date Completed: 20120815 Latest Revision: 20120403 |
| رمز التحديث: | 20231215 |
| DOI: | 10.3109/15513815.2012.656829 |
| PMID: | 22413908 |
| قاعدة البيانات: | MEDLINE |
PDF full text from Publisher | تدمد: | 1551-3823 |
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| DOI: | 10.3109/15513815.2012.656829 |