دورية أكاديمية
Dopamine-secreting carotid body paragangliomas-biochemical control with radiotherapy.
| العنوان: | Dopamine-secreting carotid body paragangliomas-biochemical control with radiotherapy. |
|---|---|
| المؤلفون: | Soh AW; Department of Endocrinology, Singapore General Hospital, Singapore. abel.soh@sgh.com.sg, Kek PC |
| المصدر: | Internal medicine (Tokyo, Japan) [Intern Med] 2012; Vol. 51 (6), pp. 613-8. Date of Electronic Publication: 2012 Mar 15. |
| نوع المنشور: | Case Reports; Journal Article; Review |
| اللغة: | English |
| بيانات الدورية: | Publisher: Japanese Society of Internal Medicine Country of Publication: Japan NLM ID: 9204241 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1349-7235 (Electronic) Linking ISSN: 09182918 NLM ISO Abbreviation: Intern Med Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: Tokyo, Japan : Japanese Society of Internal Medicine, [1992- |
| مواضيع طبية MeSH: | Carotid Body Tumor/*metabolism , Dopamine/*metabolism , Neoplasms, Multiple Primary/*metabolism, 3-Iodobenzylguanidine ; Carotid Body Tumor/diagnosis ; Carotid Body Tumor/diagnostic imaging ; Carotid Body Tumor/radiotherapy ; Disease Management ; Dopamine/urine ; Humans ; Iodine Radioisotopes ; Magnetic Resonance Angiography ; Male ; Middle Aged ; Neoplasms, Multiple Primary/diagnosis ; Neoplasms, Multiple Primary/diagnostic imaging ; Neoplasms, Multiple Primary/radiotherapy ; Radionuclide Imaging ; Radiopharmaceuticals ; Remission Induction ; Tomography, X-Ray Computed |
| مستخلص: | Head and neck paragangliomas that are exclusively or predominantly dopamine-secreting are rare. Surgery and/or radiotherapy are modalities for locoregional tumoral control. Little is known about the efficacy of radiotherapy for biochemical control in such tumors. We report a 62-year-old Chinese man with bilateral carotid body tumors which were exclusively dopamine secreting. The left-sided tumor invaded the skull base and encased the left carotid artery. Surgery was not performed due to high risk of morbidity and mortality. The patient received external beam radiotherapy to bilateral neck regions. Progressive decline and eventual normalization of urinary dopamine excretion was seen together with a slight reduction in tumor size. This is the first report demonstrating the efficacy of radiotherapy for both biochemical and locoregional control of functioning carotid body paragangliomas. |
| المشرفين على المادة: | 0 (Iodine Radioisotopes) 0 (Radiopharmaceuticals) 35MRW7B4AD (3-Iodobenzylguanidine) VTD58H1Z2X (Dopamine) |
| تواريخ الأحداث: | Date Created: 20120328 Date Completed: 20120816 Latest Revision: 20190606 |
| رمز التحديث: | 20221213 |
| DOI: | 10.2169/internalmedicine.51.6324 |
| PMID: | 22449670 |
| قاعدة البيانات: | MEDLINE |
| تدمد: | 1349-7235 |
|---|---|
| DOI: | 10.2169/internalmedicine.51.6324 |