دورية أكاديمية

Intestinal and multivisceral transplantation in patients with chronic intestinal failure.

التفاصيل البيبلوغرافية
العنوان: Intestinal and multivisceral transplantation in patients with chronic intestinal failure.
المؤلفون: Bentdal ØH; Section for Transplantation Surgery, Department of Paediatric Medicine, Oslo University Hospital, Rikshospitalet, Norway. obentdal@ous-hf.no, Foss A, Østensen AB, Lundin K, Farstad IN, Line PD
المصدر: Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke [Tidsskr Nor Laegeforen] 2012 Mar 27; Vol. 132 (6), pp. 650-4.
نوع المنشور: Journal Article
اللغة: English; Norwegian
بيانات الدورية: Publisher: Norske Laegeforening Country of Publication: Norway NLM ID: 0413423 Publication Model: Print Cited Medium: Internet ISSN: 0807-7096 (Electronic) Linking ISSN: 00292001 NLM ISO Abbreviation: Tidsskr Nor Laegeforen Subsets: MEDLINE
أسماء مطبوعة: Publication: Oslo : Norske Laegeforening
Original Publication: Chistiania : Alb. Cammermeyer, 1880-
مواضيع طبية MeSH: Intestinal Diseases/*surgery , Intestines/*transplantation, Adult ; Child, Preschool ; Duodenum/transplantation ; Female ; Florida ; Follow-Up Studies ; Graft Rejection/etiology ; Humans ; International Cooperation ; Intestine, Small/transplantation ; Kidney Transplantation ; Liver Transplantation ; Male ; Middle Aged ; Norway ; Pancreas Transplantation ; Postoperative Complications/etiology ; Short Bowel Syndrome/surgery ; Stomach/transplantation ; Treatment Outcome
مستخلص: Background: Patients with chronic intestinal failure are treated primarily with parenteral nutrition, often for many years. If serious complications arise for intravenous nutritional therapy, it is possible to perform intestinal or multi-organ transplantation in selected patients. We have established a collaboration with Professor Michael Olausson at Sahlgrenska University Hospital in Gothenburg and Professor Andreas Tzakis at the Jackson Memorial Hospital in Miami, USA, to provide an option for Norwegian patients with chronic intestinal failure.
Material and Method: Retrospective long-term study of seven patients (five in Gothenburg and two in Miami) with chronic intestinal failure who underwent intestinal or multi-organ transplantation (ventricle, duodenum, pancreas and small intestine) in the period 2001-2009. At the same time, liver and kidney transplantations were performed on six and two patients, respectively.
Results: Four of seven patients are alive and have a good quality of life 24-120 months after the transplantation. The graft function is satisfactory, so that the patients' food intake is mainly oral. Three patients died following a serious infection one, ten and 24 months, respectively, after transplantation took place.
Interpretation: Intestinal and multi-organ transplantation is a demanding and expensive treatment. Life-long multi-disciplinary follow-up of the patients is necessary after the transplantation in order to ensure early diagnosis of rejection and infections. Collaboration with international centres has given Norwegian patients with chronic intestinal failure an option of transplantation with satisfactory long-term results.
تواريخ الأحداث: Date Created: 20120330 Date Completed: 20121120 Latest Revision: 20120329
رمز التحديث: 20221213
DOI: 10.4045/tidsskr.11.0817
PMID: 22456144
قاعدة البيانات: MEDLINE
الوصف
تدمد:0807-7096
DOI:10.4045/tidsskr.11.0817