دورية أكاديمية

Facile preparation of amine and amino acid adducts of [60]fullerene using chlorofullerene C60Cl6 as a precursor.

التفاصيل البيبلوغرافية
العنوان: Facile preparation of amine and amino acid adducts of [60]fullerene using chlorofullerene C60Cl6 as a precursor.
المؤلفون: Kornev AB; IPCP RAS, Semenov Prospect 1, Chernogolovka 141432, Russia., Khakina EA, Troyanov SI, Kushch AA, Peregudov A, Vasilchenko A, Deryabin DG, Martynenko VM, Troshin PA
المصدر: Chemical communications (Cambridge, England) [Chem Commun (Camb)] 2012 Jun 04; Vol. 48 (44), pp. 5461-3. Date of Electronic Publication: 2012 Apr 26.
نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't
اللغة: English
بيانات الدورية: Publisher: Royal Society of Chemistry Country of Publication: England NLM ID: 9610838 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1364-548X (Electronic) Linking ISSN: 13597345 NLM ISO Abbreviation: Chem Commun (Camb) Subsets: MEDLINE
أسماء مطبوعة: Original Publication: Cambridge : Royal Society of Chemistry
مواضيع طبية MeSH: Amines/*chemistry , Amino Acids/*chemistry , Anti-Bacterial Agents/*chemical synthesis , Antiviral Agents/*chemical synthesis , Fullerenes/*chemistry, Animals ; Anti-Bacterial Agents/pharmacology ; Antiviral Agents/pharmacology ; Bacillus subtilis/drug effects ; Bacillus subtilis/growth & development ; Cations ; Chlorocebus aethiops ; Crystallography, X-Ray ; Cytomegalovirus/drug effects ; Cytomegalovirus/physiology ; Escherichia coli/drug effects ; Escherichia coli/growth & development ; Fibroblasts/drug effects ; Fibroblasts/virology ; Humans ; Injections, Intraperitoneal ; Lethal Dose 50 ; Magnetic Resonance Spectroscopy ; Mice ; Simplexvirus/drug effects ; Simplexvirus/physiology ; Vero Cells/drug effects ; Vero Cells/virology
مستخلص: We report a general synthetic approach to the preparation of highly functionalized amine and amino acid derivatives of [60]fullerene starting from readily available chlorofullerene C(60)Cl(6). The synthesized water-soluble amino acid derivative of C(60) demonstrated pronounced antiviral activity, while the cationic amine-based compound showed strong antibacterial action in vitro.
المشرفين على المادة: 0 (Amines)
0 (Amino Acids)
0 (Anti-Bacterial Agents)
0 (Antiviral Agents)
0 (Cations)
0 (Fullerenes)
NP9U26B839 (fullerene C60)
تواريخ الأحداث: Date Created: 20120428 Date Completed: 20120904 Latest Revision: 20191210
رمز التحديث: 20231215
DOI: 10.1039/c2cc00071g
PMID: 22540119
قاعدة البيانات: MEDLINE
الوصف
تدمد:1364-548X
DOI:10.1039/c2cc00071g