دورية أكاديمية
Facile preparation of amine and amino acid adducts of [60]fullerene using chlorofullerene C60Cl6 as a precursor.
العنوان: | Facile preparation of amine and amino acid adducts of [60]fullerene using chlorofullerene C60Cl6 as a precursor. |
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المؤلفون: | Kornev AB; IPCP RAS, Semenov Prospect 1, Chernogolovka 141432, Russia., Khakina EA, Troyanov SI, Kushch AA, Peregudov A, Vasilchenko A, Deryabin DG, Martynenko VM, Troshin PA |
المصدر: | Chemical communications (Cambridge, England) [Chem Commun (Camb)] 2012 Jun 04; Vol. 48 (44), pp. 5461-3. Date of Electronic Publication: 2012 Apr 26. |
نوع المنشور: | Journal Article; Research Support, Non-U.S. Gov't |
اللغة: | English |
بيانات الدورية: | Publisher: Royal Society of Chemistry Country of Publication: England NLM ID: 9610838 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1364-548X (Electronic) Linking ISSN: 13597345 NLM ISO Abbreviation: Chem Commun (Camb) Subsets: MEDLINE |
أسماء مطبوعة: | Original Publication: Cambridge : Royal Society of Chemistry |
مواضيع طبية MeSH: | Amines/*chemistry , Amino Acids/*chemistry , Anti-Bacterial Agents/*chemical synthesis , Antiviral Agents/*chemical synthesis , Fullerenes/*chemistry, Animals ; Anti-Bacterial Agents/pharmacology ; Antiviral Agents/pharmacology ; Bacillus subtilis/drug effects ; Bacillus subtilis/growth & development ; Cations ; Chlorocebus aethiops ; Crystallography, X-Ray ; Cytomegalovirus/drug effects ; Cytomegalovirus/physiology ; Escherichia coli/drug effects ; Escherichia coli/growth & development ; Fibroblasts/drug effects ; Fibroblasts/virology ; Humans ; Injections, Intraperitoneal ; Lethal Dose 50 ; Magnetic Resonance Spectroscopy ; Mice ; Simplexvirus/drug effects ; Simplexvirus/physiology ; Vero Cells/drug effects ; Vero Cells/virology |
مستخلص: | We report a general synthetic approach to the preparation of highly functionalized amine and amino acid derivatives of [60]fullerene starting from readily available chlorofullerene C(60)Cl(6). The synthesized water-soluble amino acid derivative of C(60) demonstrated pronounced antiviral activity, while the cationic amine-based compound showed strong antibacterial action in vitro. |
المشرفين على المادة: | 0 (Amines) 0 (Amino Acids) 0 (Anti-Bacterial Agents) 0 (Antiviral Agents) 0 (Cations) 0 (Fullerenes) NP9U26B839 (fullerene C60) |
تواريخ الأحداث: | Date Created: 20120428 Date Completed: 20120904 Latest Revision: 20191210 |
رمز التحديث: | 20231215 |
DOI: | 10.1039/c2cc00071g |
PMID: | 22540119 |
قاعدة البيانات: | MEDLINE |
تدمد: | 1364-548X |
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DOI: | 10.1039/c2cc00071g |