دورية أكاديمية
Steroid pulse therapy combined with plasmapheresis for clinically compromised patients after heart transplantation.
| العنوان: | Steroid pulse therapy combined with plasmapheresis for clinically compromised patients after heart transplantation. |
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| المؤلفون: | Chou HW; Department of Surgery, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan., Chi NH, Lin MH, Chou NK, Tsao CI, Yu HY, Chen YS, Wang SS |
| المصدر: | Transplantation proceedings [Transplant Proc] 2012 May; Vol. 44 (4), pp. 900-2. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Elsevier Science Inc Country of Publication: United States NLM ID: 0243532 Publication Model: Print Cited Medium: Internet ISSN: 1873-2623 (Electronic) Linking ISSN: 00411345 NLM ISO Abbreviation: Transplant Proc Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: New York, N.Y. : Elsevier Science Inc. Original Publication: New York Stratton. |
| مواضيع طبية MeSH: | Plasmapheresis*, Graft Rejection/*therapy , Heart Diseases/*therapy , Heart Transplantation/*adverse effects , Immunosuppressive Agents/*administration & dosage , Steroids/*administration & dosage, Combined Modality Therapy ; Graft Rejection/etiology ; Graft Rejection/mortality ; Graft Rejection/physiopathology ; Heart Diseases/etiology ; Heart Diseases/mortality ; Heart Diseases/physiopathology ; Heart Transplantation/mortality ; Hemodynamics ; Hospital Mortality ; Humans ; Myocardial Contraction ; Pulse Therapy, Drug ; Stroke Volume ; Taiwan ; Time Factors ; Treatment Outcome ; Ventricular Function, Left |
| مستخلص: | Background: The most serious complication after heart transplantation is allograft dysfunction. Patients presenting with compromised hemodynamics show a high incidence of mortality. The most common reason for allograft dysfunction is rejection. We have employed steroid pulse therapy combined with plasmapheresis for hemodynamically compromised patients after heart transplantation. Methods and Results: Steroid pulse therapy and plasmapheresis were performed on 35 patients who underwent orthotopic heart transplantation for graft dysfunction. Thus treatment rescued ventricular function and improved the ejection fraction in 77% of patients, among who ever 71.4% showed improved New York Heart Association (NYHA) functional class. Conclusions: Steroid pulse therapy combined with plasmapheresis improved the cardiac contractility and NYHA functional class of most heart transplant recipients with graft dysfunction. (Copyright © 2012 Elsevier Inc. All rights reserved.) |
| المشرفين على المادة: | 0 (Immunosuppressive Agents) 0 (Steroids) |
| تواريخ الأحداث: | Date Created: 20120509 Date Completed: 20120904 Latest Revision: 20120508 |
| رمز التحديث: | 20221213 |
| DOI: | 10.1016/j.transproceed.2012.01.086 |
| PMID: | 22564579 |
| قاعدة البيانات: | MEDLINE |
Full Text via ClinicalKey 
Full Text Finder | تدمد: | 1873-2623 |
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| DOI: | 10.1016/j.transproceed.2012.01.086 |