دورية أكاديمية
Relieving the pruritus of atopic dermatitis: a meta-analysis.
| العنوان: | Relieving the pruritus of atopic dermatitis: a meta-analysis. |
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| المؤلفون: | Sher LG; Department of Dermatology, Wake Forest School of Medicine, Winston-Salem, NC 27157, USA., Chang J, Patel IB, Balkrishnan R, Fleischer AB Jr |
| المصدر: | Acta dermato-venereologica [Acta Derm Venereol] 2012 Sep; Vol. 92 (5), pp. 455-61. |
| نوع المنشور: | Journal Article; Meta-Analysis; Research Support, Non-U.S. Gov't; Review |
| اللغة: | English |
| بيانات الدورية: | Publisher: MJS Publishing Country of Publication: Sweden NLM ID: 0370310 Publication Model: Print Cited Medium: Internet ISSN: 1651-2057 (Electronic) Linking ISSN: 00015555 NLM ISO Abbreviation: Acta Derm Venereol Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: 2024- : Uppsala, Sweden : MJS Publishing Original Publication: Stockholm : Acta dermato-venereologica |
| مواضيع طبية MeSH: | Antipruritics/*therapeutic use , Dermatitis, Atopic/*drug therapy , Pruritus/*drug therapy, Adrenal Cortex Hormones/therapeutic use ; Antipruritics/administration & dosage ; Calcineurin Inhibitors ; Dermatitis, Atopic/complications ; Drug Administration Routes ; Histamine Antagonists/therapeutic use ; Humans ; Immunosuppressive Agents/therapeutic use ; Pruritus/etiology ; Randomized Controlled Trials as Topic ; Treatment Outcome |
| مستخلص: | The goal of this study was to perform a meta-analysis on randomized controlled trials of topical therapies compared against their vehicles, and systemic therapies compared against their placebos, and to record how these therapies changed the magnitude of pruritus associated with atopic dermatitis. A systematic search of the literature was performed using Medline, Embase, and the Cochrane Controlled Clinical Trials Register, as well as follow-up references in retrieved articles. Data regarding the magnitude of the change in pruritus was extracted from eligible publications and categorized according to the type of treatment modality. Standard inverse variance fixed-effects meta-analysis was used to calculate the pooled estimates for randomized controlled trials falling under each type of treatment. Overall, the topical treatments were more successful at reducing atopic pruritus compared to the systemic treatments. Calcineurin inhibitors were the most effective antipruritic agent. |
| المشرفين على المادة: | 0 (Adrenal Cortex Hormones) 0 (Antipruritics) 0 (Calcineurin Inhibitors) 0 (Histamine Antagonists) 0 (Immunosuppressive Agents) |
| تواريخ الأحداث: | Date Created: 20120710 Date Completed: 20130322 Latest Revision: 20141120 |
| رمز التحديث: | 20221213 |
| DOI: | 10.2340/00015555-1360 |
| PMID: | 22773026 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 1651-2057 |
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| DOI: | 10.2340/00015555-1360 |