دورية أكاديمية
The efficacy of laser-assisted hair removal in the treatment of acne keloidalis nuchae; a pilot study.
| العنوان: | The efficacy of laser-assisted hair removal in the treatment of acne keloidalis nuchae; a pilot study. |
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| المؤلفون: | Esmat SM; Dermatology Department, Faculty of Medicine, Cairo University, 13th Abrag Othman, Kornish El Maadi, Cairo 11431, Egypt., Abdel Hay RM, Abu Zeid OM, Hosni HN |
| المصدر: | European journal of dermatology : EJD [Eur J Dermatol] 2012 Sep-Oct; Vol. 22 (5), pp. 645-50. |
| نوع المنشور: | Clinical Trial; Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: John Libbey Eurotext Country of Publication: France NLM ID: 9206420 Publication Model: Print Cited Medium: Internet ISSN: 1952-4013 (Electronic) Linking ISSN: 11671122 NLM ISO Abbreviation: Eur J Dermatol Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: Montrouge, France : John Libbey Eurotext, c1991- |
| مواضيع طبية MeSH: | Hair Removal*/adverse effects, Acne Keloid/*pathology , Acne Keloid/*surgery , Lasers, Solid-State/*therapeutic use , Skin/*pathology, Acne Keloid/complications ; Adult ; Biopsy ; Erythema/complications ; Follow-Up Studies ; Humans ; Lasers, Solid-State/adverse effects ; Male ; Middle Aged ; Pilot Projects ; Severity of Illness Index ; Statistics, Nonparametric ; Treatment Outcome ; Young Adult |
| مستخلص: | Background: Laser-assisted hair removal causes miniaturization of hair shafts which are the principal contributors to inflammation in acne keloidalis nuchae (AKN). Objective: To assess the efficacy of hair reduction by long pulsed Nd-YAG laser as a therapeutic modality for AKN. Methods: This interventional pilot trial included 16 patients with AKN who received 5 sessions of long pulsed Nd-YAG laser. Lesions were objectively and subjectively assessed at the third and fifth laser sessions, and 1 year after. Global response to treatment was rated using a quartile grading scale regarding the percentage improvement in the count of papules and the size of the plaques. Biopsies were taken before and 2 weeks after the fifth session to evaluate the pathological changes associated with improvement of the treated lesions. Results: All patients showed a significant improvement. The percentage of improvement in the early caseswas significantly higher when compared to late cases.Two weeks after the fifth session, all biopsies showed a significant decrease in the inflammatory infiltrate except one case. Sclerosis was markedly decreased. Complete absence of hair follicles and adenexawas observed, apart from in 2 cases. Conclusion: Laser hair depilation can significantly improve this disfiguring chronic disorder. Starting treatment as early as possible achieves the best results and can stop the disease process if followed by maintenance sessions. |
| تواريخ الأحداث: | Date Created: 20120929 Date Completed: 20130506 Latest Revision: 20121024 |
| رمز التحديث: | 20240628 |
| DOI: | 10.1684/ejd.2012.1830 |
| PMID: | 23018044 |
| قاعدة البيانات: | MEDLINE |
| تدمد: | 1952-4013 |
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| DOI: | 10.1684/ejd.2012.1830 |