دورية أكاديمية

Chlamydia trachomatis: a major agent of respiratory infections in infants from low-income families.

التفاصيل البيبلوغرافية
العنوان: Chlamydia trachomatis: a major agent of respiratory infections in infants from low-income families.
المؤلفون: Souza EL; Universidade Federal da Bahia, Salvador, BA, Brazil., Girão RS, Simões JM, Reis CF, Galvão NA, Andrade SC, Werneck DM, Araújo-Neto CA, Souza LS
المصدر: Jornal de pediatria [J Pediatr (Rio J)] 2012 Sep-Oct; Vol. 88 (5), pp. 423-9.
نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't
اللغة: English; Portuguese
بيانات الدورية: Publisher: Elsevier Editora Ltda Country of Publication: Brazil NLM ID: 2985188R Publication Model: Print Cited Medium: Internet ISSN: 1678-4782 (Electronic) Linking ISSN: 00217557 NLM ISO Abbreviation: J Pediatr (Rio J) Subsets: MEDLINE
أسماء مطبوعة: Publication: Rio de Janeiro, Brazil : Elsevier Editora Ltda
Original Publication: Rio de Janeiro.
مواضيع طبية MeSH: Chlamydia trachomatis*, Bronchiolitis/*epidemiology , Chlamydia Infections/*epidemiology , Chlamydial Pneumonia/*epidemiology , Poverty/*statistics & numerical data, Brazil/epidemiology ; Bronchiolitis/diagnosis ; Bronchiolitis/microbiology ; Chlamydial Pneumonia/diagnosis ; Cross-Sectional Studies ; Enzyme-Linked Immunosorbent Assay ; Female ; Hospitalization/statistics & numerical data ; Hospitals, Public/statistics & numerical data ; Humans ; Infant ; Infant, Newborn ; Male ; Prevalence
مستخلص: Objectives: To determine the prevalence of lower respiratory tract infection (LRTI) due to Chlamydia trachomatis in newborn infants and to describe the clinical, laboratory, and radiological characteristics of the disease.
Methods: A cross-sectional study carried out over a 12-month period. All infants up to 6 months of age admitted consecutively at the Centro Pediátrico Professor Hosannah de Oliveira of the Universidade Federal da Bahia in Salvador, Brazil, and diagnosed with LRTI according to clinical and/or radiological criteria were included in the study. C. trachomatis infection was diagnosed by the enzyme-linked immunosorbent assay (ELISA) for the detection of IgM-class antibodies. The prevalence of LRTI by C. trachomatis was determined and the prevalence ratios for the infection and clinical or laboratory variables were calculated.
Results: One hundred and fifty-one infants were submitted to serology for C. trachomatis and 15 (9.9%) tested positive. Chlamydial infection was found only in infants under 5 months of age, mainly in those aged under 2 months. Three of the infants with C. trachomatis infection were born by cesarean section. Conjunctivitis and eosinophilia had occurred in 33.3% of the cases. Chest X rays were abnormal in 92.0% of cases. There was an association between C. trachomatis infection and the duration of hospitalization exceeding 15 days (p = 0.0398) and oxygen therapy (p = 0.0484).
Conclusions: There was a high prevalence of C. trachomatis respiratory infection in the population studied. The infection was associated with a more severe form of the disease, emphasizing the importance of testing pregnant women for this infection to avoid infection in the newborn infant.
تواريخ الأحداث: Date Created: 20121025 Date Completed: 20130507 Latest Revision: 20200413
رمز التحديث: 20231215
DOI: 10.2223/JPED.2224
PMID: 23093203
قاعدة البيانات: MEDLINE
الوصف
تدمد:1678-4782
DOI:10.2223/JPED.2224