دورية أكاديمية
أعرض في EDS

Human african trypanosomiasis diagnosis in first-line health services of endemic countries, a systematic review.

التفاصيل البيبلوغرافية
العنوان: Human african trypanosomiasis diagnosis in first-line health services of endemic countries, a systematic review.
المؤلفون: Mitashi P; Department of Tropical Medicine, Parasitology Service, Faculty of Medicine, Kinshasa University, Kinshasa, Democratic Republic of Congo., Hasker E, Lejon V, Kande V, Muyembe JJ, Lutumba P, Boelaert M
المصدر: PLoS neglected tropical diseases [PLoS Negl Trop Dis] 2012; Vol. 6 (11), pp. e1919. Date of Electronic Publication: 2012 Nov 29.
نوع المنشور: Journal Article; Review; Systematic Review
اللغة: English
بيانات الدورية: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101291488 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1935-2735 (Electronic) Linking ISSN: 19352727 NLM ISO Abbreviation: PLoS Negl Trop Dis Subsets: MEDLINE
أسماء مطبوعة: Original Publication: San Francisco, CA : Public Library of Science
مواضيع طبية MeSH: Endemic Diseases*, Diagnostic Tests, Routine/*methods , Parasitology/*methods , Trypanosomiasis, African/*diagnosis , Trypanosomiasis, African/*epidemiology, Humans
مستخلص: While the incidence of Human African Trypanosomiasis (HAT) is decreasing, the control approach is shifting from active population screening by mobile teams to passive case detection in primary care centers. We conducted a systematic review of the literature between 1970 and 2011 to assess which diagnostic tools are most suitable for use in first-line health facilities in endemic countries. Our search retrieved 16 different screening and confirmation tests for HAT. The thermostable format of the Card Agglutination Test for Trypanosomiasis (CATT test) was the most appropriate screening test. Lateral flow antibody detection tests could become alternative screening tests in the near future. Confirmation of HAT diagnosis still depends on visualizing the parasite in direct microscopy. All other currently available confirmation tests are either technically too demanding and/or lack sensitivity and thus rather inappropriate for use at health center level. Novel applications of molecular tests may have potential for use at district hospital level.
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تواريخ الأحداث: Date Created: 20121205 Date Completed: 20130405 Latest Revision: 20220321
رمز التحديث: 20240513
مُعرف محوري في PubMed: PMC3510092
DOI: 10.1371/journal.pntd.0001919
PMID: 23209860
قاعدة البيانات: MEDLINE
الوصف
تدمد:1935-2735
DOI:10.1371/journal.pntd.0001919