دورية أكاديمية
أعرض في EDS

In vivo detection and quantification of chemicals that enhance protein stability.

التفاصيل البيبلوغرافية
العنوان: In vivo detection and quantification of chemicals that enhance protein stability.
المؤلفون: Hailu TT; Howard Hughes Medical Institute, Department of Molecular, Cellular, and Developmental Biology, University of Michigan, Ann Arbor, MI 48109, USA., Foit L, Bardwell JC
المصدر: Analytical biochemistry [Anal Biochem] 2013 Mar 01; Vol. 434 (1), pp. 181-6. Date of Electronic Publication: 2012 Dec 05.
نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't
اللغة: English
بيانات الدورية: Publisher: Elsevier Country of Publication: United States NLM ID: 0370535 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1096-0309 (Electronic) Linking ISSN: 00032697 NLM ISO Abbreviation: Anal Biochem Subsets: MEDLINE
أسماء مطبوعة: Publication: <2000- > : San Diego, CA : Elsevier
Original Publication: Orlando Fl : Academic Press
مواضيع طبية MeSH: Colorimetry*, Carbohydrates/*analysis , Caseins/*analysis , Lipids/*analysis , Plant Proteins, Dietary/*analysis , beta-Lactamases/*metabolism, Escherichia coli/metabolism ; Molecular Chaperones/metabolism ; Protein Folding ; Protein Stability ; beta-Lactamases/chemistry
مستخلص: We have devised protein-folding sensors that link protein stability to TEM-1 β-lactamase activity. The addition of osmolytes and other compounds with chemical chaperone activity to the growth medium of bacteria containing these sensors increases β-lactamase activity up to 207-fold in a dose-dependent manner. This enables the rapid detection and sensitive quantification of compounds that enhance in vivo protein stability.
(Copyright © 2012 Elsevier Inc. All rights reserved.)
References: Perspect Medicin Chem. 2007 Dec 11;1:39-48. (PMID: 19812735)
Biochim Biophys Acta. 2006 Nov;1764(11):1677-87. (PMID: 17046342)
Proc Natl Acad Sci U S A. 2006 Sep 19;103(38):13997-4002. (PMID: 16968772)
Mol Genet Metab. 2001 Jun;73(2):173-8. (PMID: 11386853)
Genome Res. 2003 Aug;13(8):1938-43. (PMID: 12869575)
Handb Exp Pharmacol. 2006;(172):405-16. (PMID: 16610368)
Microbiol Mol Biol Rev. 2003 Dec;67(4):593-656. (PMID: 14665678)
Mol Cell. 2009 Dec 11;36(5):861-71. (PMID: 20005848)
J Biol Chem. 2005 Apr 22;280(16):15553-60. (PMID: 15695514)
Proc Natl Acad Sci U S A. 2007 Aug 7;104(32):13192-7. (PMID: 17670938)
Protein Sci. 2010 May;19(5):929-43. (PMID: 20198681)
Nature. 2003 Dec 18;426(6968):905-9. (PMID: 14685252)
Nat Struct Biol. 2002 Mar;9(3):209-16. (PMID: 11875516)
Neurobiol Dis. 2010 Oct;40(1):12-20. (PMID: 20472062)
Methods Mol Biol. 2009;490:135-64. (PMID: 19157082)
J Exp Biol. 2005 Aug;208(Pt 15):2819-30. (PMID: 16043587)
Biopolymers. 2007;88(2):157-63. (PMID: 17206628)
Biophys J. 2004 Oct;87(4):2656-62. (PMID: 15454460)
Nat Biotechnol. 2002 Jun;20(6):619-22. (PMID: 12042868)
Nat Struct Mol Biol. 2011 Mar;18(3):262-9. (PMID: 21317898)
Annu Rev Microbiol. 1991;45:569-606. (PMID: 1741624)
Nat Struct Biol. 1999 Apr;6(4):380-7. (PMID: 10201408)
Proc Natl Acad Sci U S A. 2006 Aug 15;103(33):12394-9. (PMID: 16894178)
J Biol Chem. 2010 May 21;285(21):15866-73. (PMID: 20308073)
J Chem Phys. 2010 Jun 14;132(22):225103. (PMID: 20550422)
Nature. 2000 Apr 13;404(6779):770-4. (PMID: 10783891)
FEBS J. 2007 Nov;274(22):6000-10. (PMID: 17983358)
Biochemistry. 2010 Feb 16;49(6):1310-8. (PMID: 20073511)
Comp Biochem Physiol A Mol Integr Physiol. 2002 Nov;133(3):667-76. (PMID: 12443924)
Annu Rev Phys Chem. 2010;61:63-83. (PMID: 20055667)
Nat Struct Mol Biol. 2009 Jun;16(6):574-81. (PMID: 19491934)
Biochemistry. 2009 Nov 24;48(46):11084-96. (PMID: 19817484)
معلومات مُعتمدة: United States HHMI_ Howard Hughes Medical Institute
فهرسة مساهمة: Indexing Agency: NLM Local ID #: HHMIMS458709.
المشرفين على المادة: 0 (Carbohydrates)
0 (Caseins)
0 (Lipids)
0 (Molecular Chaperones)
0 (Plant Proteins, Dietary)
102257-18-1 (Osmolite)
EC 3.5.2.6 (beta-Lactamases)
EC 3.5.2.6 (beta-lactamase TEM-1)
تواريخ الأحداث: Date Created: 20121211 Date Completed: 20130814 Latest Revision: 20230425
رمز التحديث: 20231215
مُعرف محوري في PubMed: PMC3670414
DOI: 10.1016/j.ab.2012.11.022
PMID: 23219982
قاعدة البيانات: MEDLINE
الوصف
تدمد:1096-0309
DOI:10.1016/j.ab.2012.11.022