دورية أكاديمية

Associated factors with survivals in patients undergoing orthotopic heart transplant using retrograde blood microcardioplegia.

التفاصيل البيبلوغرافية
العنوان: Associated factors with survivals in patients undergoing orthotopic heart transplant using retrograde blood microcardioplegia.
المؤلفون: Lavagnoli CF; HC, UNICAMP, Campinas, SP, Brasil. clavagnoli@gmail.com, Severino ES, Vilarinho KA, Silveira Filho Lda M, Oliveira PP, Petrucci O, Vieira RW, Braile DM
المصدر: Revista brasileira de cirurgia cardiovascular : orgao oficial da Sociedade Brasileira de Cirurgia Cardiovascular [Rev Bras Cir Cardiovasc] 2012 Jul-Sep; Vol. 27 (3), pp. 347-54.
نوع المنشور: Journal Article
اللغة: English; Portuguese
بيانات الدورية: Publisher: Sociedade Brasileira de Cirurgia Cardiovascular Country of Publication: Brazil NLM ID: 9104279 Publication Model: Print Cited Medium: Internet NLM ISO Abbreviation: Rev Bras Cir Cardiovasc Subsets: MEDLINE
أسماء مطبوعة: Original Publication: São Paulo, SP, Brasil : Sociedade Brasileira de Cirurgia Cardiovascular
مواضيع طبية MeSH: Cardioplegic Solutions* , Heart*, Heart Arrest, Induced/*methods , Heart Transplantation/*mortality , Organ Preservation/*methods, Adult ; Brazil ; Epidemiologic Methods ; Female ; Heart Transplantation/methods ; Humans ; Male ; Middle Aged ; Time Factors ; Treatment Outcome
مستخلص: Background: Several techniques and cardioplegic solutions have been used for heart preservation during transplant procedures. Unfortunately, there is a lack of ideal method for myocardial preservation in the clinical practice. The use of retrograde cardioplegia provides continuous infusion of cardioplegic solution during the graft implantation. This strategy may provide better initial recovery of the graft. The objective of this study is to describe the experience of a single center where all patients received the same solution for organ preservation and were subjected to continuous retrograde blood microcardioplegia during implantation of the graft and to evaluate factors associated to early and late mortality with this technique.
Methods: This is a retrospective, observational and descriptive study of a single center.
Results: During the study period were performed 35 heart transplants. Fifteen (42.9%) patients were in cardiogenic shock. The probability of survival was 74.8±7.8%, 60.4±11.3% and 15.1±13.4% at 1 year, 5 years and 10 years of follow-up, respectively. The median survival time was 96.6 months.
Conclusion: The use of myocardial protection with retrograde cardioplegic solution may reduce the risks associated morbidity due to cold ischemia time during the heart transplant, and we suggest that this benefit may be even greater in cases of cold ischemia time longer ensuring protection to the myocardium.
المشرفين على المادة: 0 (Cardioplegic Solutions)
تواريخ الأحداث: Date Created: 20130105 Date Completed: 20130731 Latest Revision: 20190608
رمز التحديث: 20240628
DOI: 10.5935/1678-9741.20120061
PMID: 23288174
قاعدة البيانات: MEDLINE
الوصف
DOI:10.5935/1678-9741.20120061