دورية أكاديمية
Herpes simplex virus type 2 infection among females in Enugu, Enugu State.
| العنوان: | Herpes simplex virus type 2 infection among females in Enugu, Enugu State. |
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| المؤلفون: | Ojinmah UR; College of Medicine, University of Nigeria, Enugu Campus., Nnoruka EN, Ozoh GA, Onyekonwu CL, Aguwa EN |
| المصدر: | Nigerian journal of medicine : journal of the National Association of Resident Doctors of Nigeria [Niger J Med] 2012 Oct-Dec; Vol. 21 (4), pp. 394-403. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: The Association Country of Publication: Nigeria NLM ID: 100888321 Publication Model: Print Cited Medium: Print ISSN: 1115-2613 (Print) Linking ISSN: 11152613 NLM ISO Abbreviation: Niger J Med Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: [Lagos, Nigeria] : The Association, |
| مواضيع طبية MeSH: | Herpesvirus 2, Human*/immunology, Herpes Simplex/*epidemiology, Adult ; Antibodies, Viral/analysis ; Comorbidity ; Female ; HIV Infections/epidemiology ; Herpes Simplex/immunology ; Humans ; Middle Aged ; Nigeria/epidemiology ; Syphilis/epidemiology |
| مستخلص: | Background: Herpes simplex virus type 2 infecion is life long with manifestation in a small proportion of those infected. It has presented public health concern because of its progressively increasing prevalence which some authorities say is of epidemic proportion in developing countries. Herpes simplex virus type 2 has recently been found to have synergistic effect with human immunodeficiency virus (HIV) and co-infection of the two presents more severe burden to the immunity of the victim. This leads to much morbidity and mortality with negative economic impact. In this study, we set out to determine antibody prevalence of HSV-2 in women attending skin and ante natal care [ANC] clinics in University of Nigeria Teaching Hospital [UNTH] and Enugu State University Teaching Hospital [ESUTH]. Materials and Methods: 180 female patients/clients attending skin and ANC clinics in UNTH and ESUTH were enrolled in this descriptive study. Sociodemographic data and medical history were collected using a questionnaire. They were also examined for signs of HSV 2 manifestation, other STIs and WHO staging if HIV positive. Samples were also taken for serology, Gram staining and CD4 T-lymphocyte count. Results: The prevalence of HSV 2 was found to be 77.8% (n=137) and 14.6% (n=20) had clinical diagnosis of HSV-2.The HIV and HSV-2 co-infection rate was 5.11% (n=9) and out of 11 that were HIV positive, 9 (81.82%) were HSV-2 antibody positive. The HIV prevalence in this study was 6.3%. Conclusion: Herpes simplex virus type 2 infection is common among females in Enugu, Enugu State and is commoner among those with HIV infection. |
| المشرفين على المادة: | 0 (Antibodies, Viral) |
| تواريخ الأحداث: | Date Created: 20130112 Date Completed: 20130206 Latest Revision: 20220410 |
| رمز التحديث: | 20231215 |
| PMID: | 23304946 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 1115-2613 |
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