دورية أكاديمية
[Prevalence of dyslipidemia and elevated cardiovascular risk in patients with rheumatoid arthritis].
| العنوان: | [Prevalence of dyslipidemia and elevated cardiovascular risk in patients with rheumatoid arthritis]. |
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| عنوان ترانسليتريتد: | Prevalencia de dislipemia y riesgo cardiovascular elevado en pacientes con artritis reumatoide. |
| المؤلفون: | Haye Salinas MJ; Servicio de Reumatología, Hospital Privado Centro Médico de Córdoba SA, Córdoba., Bertoli AM, Lema L, Saucedo C, Rosa J, Quintana R, Bellomio V, Aguero S, Spindler W, Tamborenea MN, Schimid M, Ceccato F, Sala JP, Paira S, Spindler A, Soriano ER, Estel BA, Caeiro F, Alvarellos A, Saurit V |
| المصدر: | Medicina [Medicina (B Aires)] 2013; Vol. 73 (1), pp. 26-30. |
| نوع المنشور: | Comparative Study; English Abstract; Journal Article |
| اللغة: | Spanish; Castilian |
| بيانات الدورية: | Publisher: Fundación Revista Medicina (Buenos Aires) Country of Publication: Argentina NLM ID: 0204271 Publication Model: Print Cited Medium: Print ISSN: 0025-7680 (Print) Linking ISSN: 00257680 NLM ISO Abbreviation: Medicina (B Aires) Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: Buenos Aires : Fundación Revista Medicina (Buenos Aires) Original Publication: Buenos Aires. |
| مواضيع طبية MeSH: | Arthritis, Rheumatoid/*complications , Cardiovascular Diseases/*etiology , Dyslipidemias/*epidemiology, Adult ; Aged ; Argentina/epidemiology ; Case-Control Studies ; Cross-Sectional Studies ; Dyslipidemias/drug therapy ; Female ; Humans ; Hypolipidemic Agents/therapeutic use ; Male ; Middle Aged ; Prevalence ; Risk Assessment ; Risk Factors |
| مستخلص: | The objectives of this study were to compare the frequency of dyslipidemia (DLP) and the elevated cardiovascular risk between rheumatoid arthritis (RA) patients and a control group, to identify disease-related factors associated with the presence of DLP and to estimate the frequency of RA patients receiving treatment for DLP. This is a cross sectional study that included 409 RA patients and 624 controls. Cardiovascular (CV) risk was determined using the Framingham score, National Cholesterol Education Program (NCEP) and the Systematic Coronary Risk Evaluation (SCORE) adapted versions according to the European League Against Rheumatism (EULAR) guidelines. DLP was defined according to the Adult Treatment Panel III (ATPIII). The frequency of CV risk was similar in RA patients and controls, except when NCEP-EULAR adapted version for RA was applied (7% vs. 2%; p = 0.00002). A 43% of patients and 47% of controls had DLP (p = 0.15). RA patients with DLP tended to have extra-articular manifestations more frequently (36% vs. 24%; p = 0.01) and higher erythrocyte sedimentation rate (ESR) (21 [13-35] vs. 18 [10-30] mm; p = 0.003). RA patients treated for DLP varied between 11% and 32% according to the definition used. Patients with RA showed an elevated CV risk only when the NCEP-EULAR definition was used. Among RA patients, those with higher ESR and the presence of extra-articular manifestations were more likely to show DLP. The vast majority of patients were not receiving treatment for DLP. |
| المشرفين على المادة: | 0 (Hypolipidemic Agents) |
| تواريخ الأحداث: | Date Created: 20130122 Date Completed: 20131211 Latest Revision: 20140104 |
| رمز التحديث: | 20221213 |
| PMID: | 23335702 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 0025-7680 |
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