دورية أكاديمية

Topography in the phrenic motoneuron nucleus demonstrated by retrograde multiple-labelling techniques.

التفاصيل البيبلوغرافية
العنوان: Topography in the phrenic motoneuron nucleus demonstrated by retrograde multiple-labelling techniques.
المؤلفون: Gordon DC; Department of Physiology, Queen's University, Kingston, Ontario, Canada., Richmond FJ
المصدر: The Journal of comparative neurology [J Comp Neurol] 1990 Feb 15; Vol. 292 (3), pp. 424-34.
نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't
اللغة: English
بيانات الدورية: Publisher: Wiley-Liss Country of Publication: United States NLM ID: 0406041 Publication Model: Print Cited Medium: Print ISSN: 0021-9967 (Print) Linking ISSN: 00219967 NLM ISO Abbreviation: J Comp Neurol Subsets: MEDLINE
أسماء مطبوعة: Publication: <2003-> : Hoboken, N.J. : Wiley-Liss
Original Publication: Philadelphia Wistar Institute of Anatomy and Biology
مواضيع طبية MeSH: Stilbamidines*, Motor Neurons/*cytology , Phrenic Nerve/*cytology, Amidines ; Animals ; Cats ; Cell Count ; Fluorescent Dyes ; Horseradish Peroxidase
مستخلص: A combination of retrograde tracing methods was employed to distinguish populations of motoneurons supplying different motor unit territories in the feline diaphragm. The compatibility of the tracers--horseradish peroxidase, fast or true blue, diamidino yellow, and fluorogold--was first assessed by applying the different tracers concurrently to separate cut branches of hindlimb and neck muscle nerves. On the basis of these initial observations fast blue, fluorogold, and horseradish peroxidase were chosen to compare the distribution of motoneurons whose axons ran in different primary branches of the phrenic nerve. Motoneurons with different target territories were extensively intermixed throughout most of the phrenic motor nucleus. However, motoneurons innervating the sternal and medial costal part of the diaphragm were distributed more densely in the rostral part of the phrenic motor pool, whereas motoneurons serving the lateral costal part were concentrated more caudally. Crural motoneurons were intermingled with costal motoneurons in the middle and caudal portions of the nucleus. Motoneurons within the phrenic nucleus are distributed in clusters. Such clusters commonly contained motoneurons labelled from two or more primary branches. Thus, the highly ordered topography of muscle units in the diaphragm is not mirrored by the intraspinal distribution of phrenic motoneurons.
المشرفين على المادة: 0 (2-hydroxy-4,4'-diamidinostilbene, methanesulfonate salt)
0 (Amidines)
0 (Fluorescent Dyes)
0 (Stilbamidines)
0 (diamidino compound 253-50)
EC 1.11.1.- (Horseradish Peroxidase)
تواريخ الأحداث: Date Created: 19900215 Date Completed: 19900626 Latest Revision: 20151119
رمز التحديث: 20240513
DOI: 10.1002/cne.902920308
PMID: 2341610
قاعدة البيانات: MEDLINE
الوصف
تدمد:0021-9967
DOI:10.1002/cne.902920308