دورية أكاديمية
Postmenopausal osteoporosis: Our experience.
| العنوان: | Postmenopausal osteoporosis: Our experience. |
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| المؤلفون: | Mehrotra RN; Department of Endocrinology, Neursosurgery, Apollo Hospital, Jubilee Hills, Hyderabad, AP, India., Ranjan A, Lath R, Ratnam R |
| المصدر: | Indian journal of endocrinology and metabolism [Indian J Endocrinol Metab] 2012 Dec; Vol. 16 (Suppl 2), pp. S421-2. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Medknow Publications] Country of Publication: India NLM ID: 101555690 Publication Model: Print Cited Medium: Print ISSN: 2230-8210 (Print) Linking ISSN: 22309500 NLM ISO Abbreviation: Indian J Endocrinol Metab Subsets: PubMed not MEDLINE |
| أسماء مطبوعة: | Original Publication: [Mumbai, India : Medknow Publications], 1997- |
| مستخلص: | Introduction: There is very little published literature about experience with osteoporosis treatment from our country. Materials and Methods: It is a retrospective analysis of first 50 patients enrolled in our clinic for osteoporosis. Postmenopausal women with T score of less than -2.5 or history suggestive fragility fracture with supportive bone mineral density (BMD) were included. Patients having hypercalcemia, abnormal renal function, myeloma and on long-term steroids were also excluded. Results: Nearly 34% subjects were below the age of 60 years, 47% of subjects were between 60 and 70 years, whereas 18% were above 70 years. Nearly 6% had family history of osteoporosis s or history of osteoporotic fractures. Nearly 20% subjects had fracture prior to starting of any treatment. A total of 86% (40/46) had evidence of Vitamin D (VD) deficiency. Nearly 80% of patients were treated with bisphosphonates, 12% were treated with injectable bisphosphonates, and 8% were treated with teriperatide. Nearly 16% patients had duration of more than 5 years of experience with bisphosphonates. Follow up BMD was available in 25 subjects. BMD had improved significantly in 68% of subjects. In 24% the BMD was stable (the change was less than least significant change (LSC)). In 8% BMD had shown a significant decline while being on treatment. Conclusion: Postmenopausal osteoporosis occurs in relatively younger women in our country. Majority of them are VD deficient. Oral bisphosphonates is the most common used drug; it is fairly well tolerated and effective. |
| References: | Am J Med. 2006 Apr;119(4 Suppl 1):S25-31. (PMID: 16563938) J Clin Densitom. 2011 Jul-Sep;14(3):237-9. (PMID: 21810531) |
| فهرسة مساهمة: | Keywords: Post menopausal osteoporosis; bisphosphonates; bone mineral density |
| تواريخ الأحداث: | Date Created: 20130409 Date Completed: 20130409 Latest Revision: 20211021 |
| رمز التحديث: | 20221213 |
| مُعرف محوري في PubMed: | PMC3603098 |
| DOI: | 10.4103/2230-8210.104115 |
| PMID: | 23565450 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 2230-8210 |
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| DOI: | 10.4103/2230-8210.104115 |