دورية أكاديمية
Effect of Solanum surattense seed on the oxidative potential of cauda epididymal spermatozoa.
| العنوان: | Effect of Solanum surattense seed on the oxidative potential of cauda epididymal spermatozoa. |
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| المؤلفون: | Thirumalai T; Post Graduate and Research Department of Zoology, Voorhees College, Physiology Wing, Vellore-632 001, Tamilnadu, India., David E, Viviyan TS, Elumalai EK |
| المصدر: | Asian Pacific journal of tropical biomedicine [Asian Pac J Trop Biomed] 2012 Jan; Vol. 2 (1), pp. 21-3. |
| نوع المنشور: | Journal Article; Research Support, Non-U.S. Gov't |
| اللغة: | English |
| بيانات الدورية: | Publisher: Asian Pacific Tropical Medicine Press Country of Publication: China NLM ID: 101557706 Publication Model: Print Cited Medium: Print ISSN: 2221-1691 (Print) Linking ISSN: 22211691 NLM ISO Abbreviation: Asian Pac J Trop Biomed Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: Sept. 2014-: Haikou, China : Asian Pacific Tropical Medicine Press Original Publication: 2011- Aug. 2014: [Singapore] : Elsevier |
| مواضيع طبية MeSH: | Antioxidants/*pharmacology , Plant Extracts/*pharmacology , Seeds/*chemistry , Solanum/*chemistry , Spermatozoa/*drug effects, Alanine Transaminase/analysis ; Animals ; Antioxidants/isolation & purification ; Aspartate Aminotransferases/analysis ; Glutamate Dehydrogenase/analysis ; Isocitrate Dehydrogenase/analysis ; Male ; Plant Extracts/isolation & purification ; Rats, Wistar ; Spermatozoa/enzymology |
| مستخلص: | Objective: To evaluate the effect of aqueous seed extract of Solanum surattense (S. surattense) on the oxidative potential of cauda epididymal spermatozoa. Methods: S. surattense seed extract was orally administered at the dosage of 10 mg/kg b.w. for 15 days, after which aspartate transferase (AST), alanine transferase (ALT), glutamate dehydrogenase (GDH), citric acid and iso-citrate dehydrogenase (ICDH) were assayed. Results: The activity levels of the enzymes AST and ALT, which are considered to be the androgenicity in the sperm suspension, were depleted in the extract fed rats. The activity level of the enzyme ICDH, was reduced significantly in the treated group (P<0.001). Conclusions: It can be concluded that the oral administration of the aqueous seed extract of S. surattense can deplete the oxidative stress of cauda epididymal spermatozoa in albino rats. |
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| فهرسة مساهمة: | Keywords: Antifertility; Contraception; Solanum surattense; Sperm Note: Original DateCompleted: 20130410 |
| المشرفين على المادة: | 0 (Antioxidants) 0 (Plant Extracts) EC 1.1.1.41 (Isocitrate Dehydrogenase) EC 1.4.1.2 (Glutamate Dehydrogenase) EC 2.6.1.1 (Aspartate Aminotransferases) EC 2.6.1.2 (Alanine Transaminase) |
| تواريخ الأحداث: | Date Created: 20130410 Date Completed: 20150302 Latest Revision: 20211021 |
| رمز التحديث: | 20221213 |
| مُعرف محوري في PubMed: | PMC3609201 |
| DOI: | 10.1016/S2221-1691(11)60183-4 |
| PMID: | 23569828 |
| قاعدة البيانات: | MEDLINE |
| تدمد: | 2221-1691 |
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| DOI: | 10.1016/S2221-1691(11)60183-4 |