دورية أكاديمية
أعرض في EDS

Onchocerciasis: the pre-control association between prevalence of palpable nodules and skin microfilariae.

التفاصيل البيبلوغرافية
العنوان: Onchocerciasis: the pre-control association between prevalence of palpable nodules and skin microfilariae.
المؤلفون: Coffeng LE; Department of Public Health, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands., Pion SD, O'Hanlon S, Cousens S, Abiose AO, Fischer PU, Remme JH, Dadzie KY, Murdoch ME, de Vlas SJ, Basáñez MG, Stolk WA, Boussinesq M
المصدر: PLoS neglected tropical diseases [PLoS Negl Trop Dis] 2013 Apr 11; Vol. 7 (4), pp. e2168. Date of Electronic Publication: 2013 Apr 11 (Print Publication: 2013).
نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't
اللغة: English
بيانات الدورية: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101291488 Publication Model: Electronic-Print Cited Medium: Internet ISSN: 1935-2735 (Electronic) Linking ISSN: 19352727 NLM ISO Abbreviation: PLoS Negl Trop Dis Subsets: MEDLINE
أسماء مطبوعة: Original Publication: San Francisco, CA : Public Library of Science
مواضيع طبية MeSH: Onchocerciasis/*diagnosis, Adolescent ; Adult ; Africa/epidemiology ; Animals ; Antiparasitic Agents/therapeutic use ; Child ; Humans ; Ivermectin/therapeutic use ; Male ; Onchocerca volvulus/pathogenicity ; Onchocerciasis/drug therapy ; Onchocerciasis/epidemiology ; Prevalence ; Skin/parasitology ; Young Adult
مستخلص: Background: The prospect of eliminating onchocerciasis from Africa by mass treatment with ivermectin has been rejuvenated following recent successes in foci in Mali, Nigeria and Senegal. Elimination prospects depend strongly on local transmission conditions and therefore on pre-control infection levels. Pre-control infection levels in Africa have been mapped largely by means of nodule palpation of adult males, a relatively crude method for detecting infection. We investigated how informative pre-control nodule prevalence data are for estimating the pre-control prevalence of microfilariae (mf) in the skin and discuss implications for assessing elimination prospects.
Methods and Findings: We analyzed published data on pre-control nodule prevalence in males aged ≥ 20 years and mf prevalence in the population aged ≥ 5 years from 148 African villages. A meta-analysis was performed by means of Bayesian hierarchical multivariate logistic regression, accounting for measurement error in mf and nodule prevalence, bioclimatic zones, and other geographical variation. There was a strong positive correlation between nodule prevalence in adult males and mf prevalence in the general population. In the forest-savanna mosaic area, the pattern in nodule and mf prevalence differed significantly from that in the savanna or forest areas.
Significance: We provide a tool to convert pre-control nodule prevalence in adult males to mf prevalence in the general population, allowing historical data to be interpreted in terms of elimination prospects and disease burden of onchocerciasis. Furthermore, we identified significant geographical variation in mf prevalence and nodule prevalence patterns warranting further investigation of geographical differences in transmission patterns of onchocerciasis.
References: Trends Parasitol. 2012 Jan;28(1):16-22. (PMID: 22079526)
Stat Med. 2003 May 30;22(10):1649-60. (PMID: 12720302)
Trans R Soc Trop Med Hyg. 2008 Feb;102(2):148-54. (PMID: 18082234)
Bull World Health Organ. 1964;31:843-55. (PMID: 14280318)
Int J Parasitol. 2011 Apr;41(5):581-9. (PMID: 21255577)
Am J Trop Med Hyg. 2006 Nov;75(5):921-7. (PMID: 17123988)
Trop Med Parasitol. 1988 Dec;39 Suppl 4:331-46. (PMID: 3067324)
Parasitology. 2000 Nov;121 Pt 5:527-34. (PMID: 11128804)
Parasit Vectors. 2012 Feb 07;5:28. (PMID: 22313631)
PLoS Negl Trop Dis. 2013;7(1):e2032. (PMID: 23383355)
Filaria J. 2003 Feb 7;2(1):2. (PMID: 12605722)
J Infect Dis. 1992 May;165(5):964-8. (PMID: 1569351)
Trop Med Parasitol. 1990 Dec;41(4):376-82. (PMID: 1963702)
West Afr J Med. 2011 Mar-Apr;30(2):104-9. (PMID: 21984457)
Comput Methods Programs Biomed. 1990 Jan;31(1):43-56. (PMID: 2311368)
PLoS Negl Trop Dis. 2012;6(9):e1825. (PMID: 23029586)
Trop Med Parasitol. 1989 Sep;40(3):340-7. (PMID: 2617045)
Trop Med Int Health. 1999 Jan;4(1):26-30. (PMID: 10203170)
Ann Trop Med Parasitol. 2002 Mar;96 Suppl 1:S29-39. (PMID: 12081248)
Trop Med Parasitol. 1989 Sep;40(3):348-54. (PMID: 2559472)
Med Vet Entomol. 2001 Jun;15(2):219-23. (PMID: 11434559)
Proc Natl Acad Sci U S A. 2005 Oct 18;102(42):15265-70. (PMID: 16217028)
Acta Leiden. 1990;59(1-2):235-52. (PMID: 2198755)
Trop Med Parasitol. 1993 Dec;44(4):311-21. (PMID: 8134773)
Am J Trop Med Hyg. 2002 Jul;67(1):128-31. (PMID: 12363057)
Bull World Health Organ. 2002;80(5):384-91. (PMID: 12077614)
Bull World Health Organ. 1997;75(3):237-45. (PMID: 9277011)
Ann Soc Belg Med Trop. 1990 Sep;70(3):193-202. (PMID: 2241307)
Vet Res. 2009 Jul-Aug;40(4):30. (PMID: 19323968)
PLoS Negl Trop Dis. 2009 Jul 21;3(7):e497. (PMID: 19621091)
معلومات مُعتمدة: United Kingdom Wellcome Trust; 092677/Z/10/Z United Kingdom WT_ Wellcome Trust
المشرفين على المادة: 0 (Antiparasitic Agents)
70288-86-7 (Ivermectin)
تواريخ الأحداث: Date Created: 20130418 Date Completed: 20131114 Latest Revision: 20220409
رمز التحديث: 20221213
مُعرف محوري في PubMed: PMC3623701
DOI: 10.1371/journal.pntd.0002168
PMID: 23593528
قاعدة البيانات: MEDLINE
الوصف
تدمد:1935-2735
DOI:10.1371/journal.pntd.0002168