دورية أكاديمية
Anterior segment optical coherence tomography parameters in subtypes of primary angle closure.
العنوان: | Anterior segment optical coherence tomography parameters in subtypes of primary angle closure. |
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المؤلفون: | Guzman CP; Singapore Eye Research Institute, Singapore National Eye Centre, Singapore., Gong T, Nongpiur ME, Perera SA, How AC, Lee HK, Cheng L, He M, Baskaran M, Aung T |
المصدر: | Investigative ophthalmology & visual science [Invest Ophthalmol Vis Sci] 2013 Aug 07; Vol. 54 (8), pp. 5281-6. Date of Electronic Publication: 2013 Aug 07. |
نوع المنشور: | Comparative Study; Journal Article; Research Support, Non-U.S. Gov't |
اللغة: | English |
بيانات الدورية: | Publisher: Association For Research In Vision And Ophthalmology (Arvo) Country of Publication: United States NLM ID: 7703701 Publication Model: Electronic Cited Medium: Internet ISSN: 1552-5783 (Electronic) Linking ISSN: 01460404 NLM ISO Abbreviation: Invest Ophthalmol Vis Sci Subsets: MEDLINE |
أسماء مطبوعة: | Publication: Brookline Ma : Association For Research In Vision And Ophthalmology (Arvo) Original Publication: St. Louis, Mosby. |
مواضيع طبية MeSH: | Anterior Eye Segment/*pathology , Glaucoma, Angle-Closure/*diagnosis , Tomography, Optical Coherence/*methods, Adult ; Aged ; Aged, 80 and over ; Diagnosis, Differential ; Female ; Follow-Up Studies ; Glaucoma, Angle-Closure/classification ; Glaucoma, Angle-Closure/physiopathology ; Gonioscopy ; Humans ; Intraocular Pressure ; Male ; Middle Aged ; Prospective Studies |
مستخلص: | Purpose: To compare anterior segment parameters, assessed by anterior segment optical coherence tomography (ASOCT), in subjects categorized as primary angle closure suspect (PACS), primary angle closure (PAC), primary angle closure glaucoma (PACG), and previous acute PAC (APAC); and to identify factors associated with APAC. Methods: This was a prospective ASOCT study of 425 subjects with angle closure (176 PACS, 66 PAC, 125 PACG, and 58 APAC). Customized software was used to measure ASOCT parameters, including angle opening distance (AOD750), trabecular-iris space area (TISA750), anterior chamber depth, width, area and volume (ACD, ACW, ACA, ACV), iris thickness (IT750), iris area (IAREA), and lens vault (LV). Mean differences in anterior segment parameters were evaluated by analysis of covariance (ANCOVA) adjusted for age, sex, and pupil diameter (PD). Results: Comparison among the different subgroups showed that ACD, ACA, and ACV were smallest, and IT750 thickest in the APAC group compared with the other subgroups (P < 0.001). LV was greatest in the APAC group (1218 ± 34 μm) followed by PAC (860 ± 31 μm), PACG (845 ± 23 μm), and PACS (804 ± 19 μm), respectively (P = <0.001). While the APAC group had the narrowest angles, the PACS group had the widest (P < 0.001 for both AOD750 and TISA750). Logistic regression showed that greater LV (P = <0.001), narrower TISA750 (P = <0.001), and thicker IT750 (P = 0.007) were the major determinants of APAC. Conclusions: Eyes with APAC had the narrowest angles, smallest anterior segment dimensions, thickest iris, and largest LV compared with PACS, PAC, and PACG. LV, TISA750, and IT750 were the major determinants of APAC. |
التعليقات: | Comment in: Invest Ophthalmol Vis Sci. 2013 Aug;54(8):5287. (PMID: 23925917) |
فهرسة مساهمة: | Keywords: anterior chamber depth; anterior segment optical coherence tomography; iris thickness; lens vault; primary angle closure subtypes |
تواريخ الأحداث: | Date Created: 20130622 Date Completed: 20130930 Latest Revision: 20220331 |
رمز التحديث: | 20240628 |
DOI: | 10.1167/iovs.13-12285 |
PMID: | 23788370 |
قاعدة البيانات: | MEDLINE |
تدمد: | 1552-5783 |
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DOI: | 10.1167/iovs.13-12285 |