دورية أكاديمية
PET or PET/CT for detection of peritoneal carcinomatosis: a meta-analysis.
| العنوان: | PET or PET/CT for detection of peritoneal carcinomatosis: a meta-analysis. |
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| المؤلفون: | Chang MC; Nuclear Medicine Department, Changhua Christian Hospital, Changhua., Chen JH, Liang JA, Huang WS, Cheng KY, Kao CH |
| المصدر: | Clinical nuclear medicine [Clin Nucl Med] 2013 Aug; Vol. 38 (8), pp. 623-9. |
| نوع المنشور: | Journal Article; Meta-Analysis |
| اللغة: | English |
| بيانات الدورية: | Publisher: Lippincott Country of Publication: United States NLM ID: 7611109 Publication Model: Print Cited Medium: Internet ISSN: 1536-0229 (Electronic) Linking ISSN: 03639762 NLM ISO Abbreviation: Clin Nucl Med Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: Philadelphia, Lippincott. |
| مواضيع طبية MeSH: | Multimodal Imaging/*methods , Peritoneal Neoplasms/*diagnostic imaging , Positron-Emission Tomography/*methods , Tomography, X-Ray Computed/*methods, Animals ; Humans |
| مستخلص: | Unlabelled: The present study assessed the diagnostic performances of (18)F-FDG PET or PET/CT in detecting peritoneal carcinomatosis in patients with cancer. Methods: Through a search of MEDLINE (January 1998 to September 2012), an overall weighted average for sensitivity and specificity was calculated using the weighted averages of the sample sizes in each relevant study. Pooled estimates of positive and negative likelihood ratios were calculated using fixed and random effects models, respectively, according to the heterogeneity among studies. A summary receiver operating characteristics (sROC) curve was constructed and the area under the sROC curve (AUC) was calculated. To explore heterogeneity, due to sources other than threshold effects, I-square was calculated. Results: The present study included analyses of patients (n = 513) from 7 studies. Results indicated a significant heterogeneity for sensitivity and specificity (I(2) > 50% and P < 0.05). The overall pooled estimates for sensitivity and specificity of FDG PET or PET/CT scans in the detection of peritoneal carcinomatosis were 72.4% (95% CI, 64.4%-79.5%) and 96.7% (95% CI, 94.4%-98.3%), respectively. The positive likelihood ratio was 10.414 (95% CI, 6.195-17.506) and the negative likelihood ratio 0.312 (95% CI, 0.159-0.612). The AUC was 0.9404. The overall diagnostic accuracy (Q* index) was 87.8%. Conclusion: The high specificity may provide the reliability of a positive FDG PET or PET/CT to detect peritoneal carcinomatosis in patients with cancer. FDG PET or PET/CT has only weak power to exclude the presence of peritoneal carcinomatosis. By a good overall diagnostic accuracy, FDG PET or PET/CT may prove beneficial to surgeons when selecting appropriate patients on whom to perform laparoscopy or laparotomy. |
| تواريخ الأحداث: | Date Created: 20130626 Date Completed: 20140127 Latest Revision: 20161125 |
| رمز التحديث: | 20240628 |
| DOI: | 10.1097/RLU.0b013e318299609f |
| PMID: | 23797225 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 1536-0229 |
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| DOI: | 10.1097/RLU.0b013e318299609f |