دورية أكاديمية
Severe secondary hyperparathyroidism and panoramic radiography parameters.
| العنوان: | Severe secondary hyperparathyroidism and panoramic radiography parameters. |
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| المؤلفون: | Henriques JC; Department of Diagnosis and Surgery, School of Dentistry, UNESP-Univ Estadual Paulista, São José dos Campos, São Paulo, Brazil, joaocesarhenriques@yahoo.com.br., de Melo Castilho JC, Jacobs R, Amorim JB, Rosa RR, Matai CV |
| المصدر: | Clinical oral investigations [Clin Oral Investig] 2014 Apr; Vol. 18 (3), pp. 941-8. Date of Electronic Publication: 2013 Jul 12. |
| نوع المنشور: | Journal Article; Research Support, Non-U.S. Gov't |
| اللغة: | English |
| بيانات الدورية: | Publisher: Springer-Verlag Country of Publication: Germany NLM ID: 9707115 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1436-3771 (Electronic) Linking ISSN: 14326981 NLM ISO Abbreviation: Clin Oral Investig |
| أسماء مطبوعة: | Publication: Berlin : Springer-Verlag Original Publication: Berlin : Springer, c1997- |
| مواضيع طبية MeSH: | Hyperparathyroidism, Secondary/*complications, Humans ; Hyperparathyroidism, Secondary/pathology ; Observer Variation ; Parathyroid Hormone/blood ; Radiography, Panoramic |
| مستخلص: | Objectives: Renal osteodystrophy (RO) are skeletal abnormalities seen in patients with secondary hyperparathyroidism (SHPT). This study aims to evaluate the effects of RO using panoramic radiography parameters. Furthermore, the correlation between these parameters and parathyroid hormone (PTH) levels was tested. Materials and Methods: Qualitative (mandibular cortical index/trabecular bone pattern) and quantitative parameters (mental index/calcification and resorption foci) were applied from panoramic radiographs of chronic kidney disease (CKD) patients and controls. Frequency distribution and descriptive analysis were used to compare the results of both groups. Spearman's correlation coefficient evaluated the correlation between serum PTH levels of CKD patients and the radiographic parameters. Intra- and interobserver agreement was tested using the intraclass correlation coefficient and kappa index. Results: Intra- and interobserver agreement was respectively excellent (0.81-1.00) and good (0.61-0.80). Qualitative parameters demonstrate significant difference compared with the control group. Mean mental index was lower in patients with CKD (3.17 ± 1.35 mm), but the difference was not significant. Calcification/resorption foci (3.63 ± 2.07) of CKD patients were significantly more present than in the control group (p = 0.0001). PTH levels were correlated with mental index, mandibular cortical index and trabecular bone pattern (respectively, 0.0034, 0.0315, and 0.0370). Conclusions: RO presented a number of characteristic bone metabolic effects in the jaws that could be observed on panoramic radiographs. Radiographs of CKD patients demonstrate significantly more calcification and resorption. Clinical Relevance: The mental index, mandibular cortical index, and trabecular bone pattern are good parameters for evaluating the effects of RO on severe secondary hyperparathyroidism. |
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| المشرفين على المادة: | 0 (Parathyroid Hormone) |
| تواريخ الأحداث: | Date Created: 20130713 Date Completed: 20160209 Latest Revision: 20211021 |
| رمز التحديث: | 20240628 |
| DOI: | 10.1007/s00784-013-1025-0 |
| PMID: | 23846212 |
| قاعدة البيانات: | MEDLINE |
Find this article in full text from Springer Verlag. 
Full Text Finder | تدمد: | 1436-3771 |
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| DOI: | 10.1007/s00784-013-1025-0 |