دورية أكاديمية
The mechanistic basis for psoriasis immunopathogenesis: translating genotype to phenotype. Report of a workshop, Venice, 2012.
العنوان: | The mechanistic basis for psoriasis immunopathogenesis: translating genotype to phenotype. Report of a workshop, Venice, 2012. |
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المؤلفون: | Bachelez H; Department of Dermatology, Saint-Louis Hospital, Sorbonne Paris Cité University Paris Diderot, Paris, France. herve.bachelez@sls.aphp.fr, Viguier M, Tebbey PW, Lowes M, Suárez-Fariñas M, Costanzo A, Nestle FO |
المصدر: | The British journal of dermatology [Br J Dermatol] 2013 Aug; Vol. 169 (2), pp. 283-6. |
نوع المنشور: | Consensus Development Conference; Journal Article; Research Support, Non-U.S. Gov't |
اللغة: | English |
بيانات الدورية: | Publisher: Oxford University Press Country of Publication: England NLM ID: 0004041 Publication Model: Print Cited Medium: Internet ISSN: 1365-2133 (Electronic) Linking ISSN: 00070963 NLM ISO Abbreviation: Br J Dermatol Subsets: MEDLINE |
أسماء مطبوعة: | Publication: 2023- : Oxford : Oxford University Press Original Publication: Oxford [etc.] Published for the British Association of Dermatologists by Blackwell Scientific Publications [etc.] |
مواضيع طبية MeSH: | Cytokines/*immunology , Psoriasis/*immunology, Adaptive Immunity/immunology ; Cytokines/genetics ; Genotype ; Humans ; Immunity, Innate/immunology ; Phenotype ; Psoriasis/genetics ; Receptors, Cytokine/genetics ; Receptors, Cytokine/immunology |
مستخلص: | The International Psoriasis Council, a global nonprofit organization dedicated to advancing psoriasis research and treatment, led an initiative to better define the pathogenic mechanisms that constitute psoriasis. In September 2012, a workshop was held at the 42nd Annual European Society for Dermatological Research in Venice, Italy. By assembling a panel of global dermatology and immunology experts, the objective was to evaluate the current status of the science explaining the mechanism of disease in psoriasis, e.g. dysregulation of the skin immune system and perturbations of epidermal homeostasis. The workshop consisted of four oral presentations, which addressed key topics in psoriasis, delivered by Hervé Bachelez (Paris, France), Antonio Costanzo (Rome, Italy), Michelle Lowes (New York, NY, U.S.A.) and Frank Nestle (London, U.K.). A global expert panel was assembled to stimulate dialogue and debate: Kevin Cooper (Cleveland, OH, U.S.A.), Michel Gilliet (Lausanne, Switzerland), Joerg Prinz (Munich, Germany), Martin Röcken (Tubingen, Germany), Jens Schroeder (Kiel, Germany), Manuelle Viguier (Paris, France), Mayte Suárez-Fariñas (New York, NY, U.S.A.) and Cristina Zielinski (Berlin, Germany). Collectively, the presentations demonstrated the significant advances in understanding immune regulation that have occurred over the past decade by virtue of the study of psoriasis subtypes, phenotypic manifestations and genetic associations. Elucidating the pathogenic and genetic basis of psoriasis holds the promise of a complete understanding of disease mechanisms, predictors of treatment response, novel drug development strategies and customized therapeutic regimens for the individual patient. (© 2013 The Authors BJD © 2013 British Association of Dermatologists.) |
معلومات مُعتمدة: | MR/J006742/1 United Kingdom MRC_ Medical Research Council |
المشرفين على المادة: | 0 (Cytokines) 0 (Receptors, Cytokine) |
تواريخ الأحداث: | Date Created: 20130815 Date Completed: 20140311 Latest Revision: 20220129 |
رمز التحديث: | 20231215 |
DOI: | 10.1111/bjd.12347 |
PMID: | 23941252 |
قاعدة البيانات: | MEDLINE |
تدمد: | 1365-2133 |
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DOI: | 10.1111/bjd.12347 |