دورية أكاديمية

Mineralizing angiopathy with infantile basal ganglia stroke after minor trauma.

التفاصيل البيبلوغرافية
العنوان: Mineralizing angiopathy with infantile basal ganglia stroke after minor trauma.
المؤلفون: Lingappa L; Department of Pediatric Neurology, Rainbow Hospital for Women and Children, Hyderabad, India., Varma RD, Siddaiahgari S, Konanki R
المصدر: Developmental medicine and child neurology [Dev Med Child Neurol] 2014 Jan; Vol. 56 (1), pp. 78-84. Date of Electronic Publication: 2013 Sep 17.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: Blackwell Country of Publication: England NLM ID: 0006761 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1469-8749 (Electronic) Linking ISSN: 00121622 NLM ISO Abbreviation: Dev Med Child Neurol Subsets: MEDLINE
أسماء مطبوعة: Publication: <2010->: Oxford : Blackwell
Original Publication: 1962- : London : National Spastics Society Medical Education and Information
مواضيع طبية MeSH: Basal Ganglia/*blood supply , Basal Ganglia Cerebrovascular Disease/*complications , Brain Injuries/*complications , Brain Ischemia/*complications , Cerebral Hemorrhage/*complications , Stroke/*complications , Stroke/*etiology , Vascular Calcification/*complications, Cerebral Veins/pathology ; Dystonia/etiology ; Female ; Follow-Up Studies ; Humans ; India ; Infant ; Magnetic Resonance Angiography ; Male ; Paresis/etiology ; Prospective Studies ; Tomography, X-Ray Computed ; Vascular Calcification/diagnostic imaging
مستخلص: Aims: The objective of this study was to describe a cohort of infants with basal ganglia stroke associated with mineralization in the lenticulostriate arteries and their clinical outcomes.
Method: Subcortical strokes occurring in infants during the study period were categorized as arterial ischaemic, venous, or haemorrhagic. A cohort of infants with basal ganglia infarcts and associated mineralization of lenticulostriate arteries were identified. This group was analysed for possible aetiological factors, clinical course, and recurrence rate of the stroke.
Results: Of 23 infants with basal ganglia arterial ischaemic stroke, 22 (16 males, six females; mean age 11mo [±SD 4.8mo]) were found to have lenticulostriate artery mineralization. Twenty infants presented with hemiparesis and two presented with recurrent episodes of hemidystonia. Eighteen infants had a history of minor trauma before onset of stroke. No other predisposing factors were identified in this cohort. There were no demonstrable causes for vascular and soft tissue calcification. The mean follow-up was 11 months, during which five infants experienced stroke recurrence. Of the 17 infants who did not experience a recurrent stroke, eight exhibited complete neurological recovery, and nine had mild residual hemiparesis.
Interpretation: Acute basal ganglia stroke after minor trauma associated with mineralization of lenticulostriate arteries in infants is a distinct clinicoradiological entity. Investigations for prothrombotic states and vasculopathies are normal. Although neurological outcomes in most children are good, trauma is a risk factor for recurrence of stroke.
(© 2013 Mac Keith Press.)
التعليقات: Comment in: Dev Med Child Neurol. 2014 Jan;56(1):9-10. (PMID: 24117103)
Comment in: Dev Med Child Neurol. 2014 Jul;56(7):699. (PMID: 24575866)
Comment in: Dev Med Child Neurol. 2014 Jul;56(7):699-700. (PMID: 24750040)
تواريخ الأحداث: Date Created: 20131010 Date Completed: 20140207 Latest Revision: 20220408
رمز التحديث: 20240628
DOI: 10.1111/dmcn.12275
PMID: 24102209
قاعدة البيانات: MEDLINE
الوصف
تدمد:1469-8749
DOI:10.1111/dmcn.12275