دورية أكاديمية
Relationship between visual acuity and spectral domain optical coherence tomography retinal parameters in neovascular age-related macular degeneration.
| العنوان: | Relationship between visual acuity and spectral domain optical coherence tomography retinal parameters in neovascular age-related macular degeneration. |
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| المؤلفون: | Ristau T; Cologne Image Reading Center, Department of Ophthalmology, University Hospital of Cologne, Cologne, Germany., Keane PA, Walsh AC, Engin A, Mokwa N, Kirchhof B, Sadda SR, Liakopoulos S |
| المصدر: | Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde [Ophthalmologica] 2014; Vol. 231 (1), pp. 37-44. Date of Electronic Publication: 2013 Oct 02. |
| نوع المنشور: | Journal Article; Research Support, Non-U.S. Gov't |
| اللغة: | English |
| بيانات الدورية: | Publisher: Karger Country of Publication: Switzerland NLM ID: 0054655 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1423-0267 (Electronic) Linking ISSN: 00303755 NLM ISO Abbreviation: Ophthalmologica Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: Basel : Karger Original Publication: Basel. |
| مواضيع طبية MeSH: | Tomography, Optical Coherence*, Macular Edema/*physiopathology , Retina/*pathology , Visual Acuity/*physiology , Wet Macular Degeneration/*physiopathology, Aged ; Atrophy ; Female ; Fluorescein Angiography ; Follow-Up Studies ; Humans ; Imaging, Three-Dimensional ; Male ; Retrospective Studies |
| مستخلص: | Purpose: Relationship between spectral domain optical coherence tomography (SD-OCT) and visual acuity (VA) in neovascular age-related macular degeneration (NVAMD). Procedures: VA and SD-OCTs of 64 treatment-naive eyes with NVAMD were retrospectively collected at baseline and 1 year (n = 30). Retinal and subretinal spaces were manually analyzed. Volume and thickness measurements were correlated with VA. Results: At baseline, lower VA correlated with increased volume of subretinal hyperreflective material (R = 0.4, p < 0.001) and with decreased volume of the photoreceptor layer (PRL, R = -0.4, p < 0.01). At 1 year, lower VA correlated with decreased volume of the retina (R = -0.7, p < 0.001), outer nuclear layer (R = -0.6, p < 0.05) and PRL (R = -0.7, p < 0.001). Decrease in VA after 1 year correlated with a decrease in PRL (R = 0.4, p < 0.05). Conclusions: Quantitative analysis of SD-OCT revealed correlations between VA and retinal and subretinal morphological changes in NVAMD. Message: Atrophy of the outer retina is an important correlate for lower VA in NVAMD. (© 2013 S. Karger AG, Basel.) |
| تواريخ الأحداث: | Date Created: 20131011 Date Completed: 20140801 Latest Revision: 20150708 |
| رمز التحديث: | 20240628 |
| DOI: | 10.1159/000354551 |
| PMID: | 24107542 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 1423-0267 |
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| DOI: | 10.1159/000354551 |