دورية أكاديمية
أعرض في EDS

Prognostic impact of lipid contents on the target lesion in patients with drug eluting stent implantation.

التفاصيل البيبلوغرافية
العنوان: Prognostic impact of lipid contents on the target lesion in patients with drug eluting stent implantation.
المؤلفون: Kumagai S; Department of Cardiology, Aichi Medical University, 1-1 Karimata, Yazako, Nagakute, Aichi, 480-1195, Japan, kumagais@aichi-med-u.ac.jp., Takashima H, Waseda K, Ando H, Suzuki A, Uetani T, Harada K, Yoshida T, Kunimura A, Shimbo Y, Kitagawa K, Harada K, Ishii H, Yoshikawa D, Matsubara T, Murohara T, Amano T
المصدر: Heart and vessels [Heart Vessels] 2014 Nov; Vol. 29 (6), pp. 761-8. Date of Electronic Publication: 2013 Oct 20.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: Springer Verlag Country of Publication: Japan NLM ID: 8511258 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1615-2573 (Electronic) Linking ISSN: 09108327 NLM ISO Abbreviation: Heart Vessels Subsets: MEDLINE
أسماء مطبوعة: Publication: Tokyo : Springer Verlag
Original Publication: Tokyo ; Secaucus, NY : Springer International, c1985-
مواضيع طبية MeSH: Coronary Artery Disease*/diagnosis , Coronary Artery Disease*/metabolism , Coronary Artery Disease*/mortality , Coronary Artery Disease*/therapy , Plaque, Atherosclerotic*/etiology , Plaque, Atherosclerotic*/metabolism , Plaque, Atherosclerotic*/pathology , Postoperative Complications*/etiology , Postoperative Complications*/metabolism , Postoperative Complications*/pathology, Angioplasty, Balloon, Coronary/*adverse effects , Lipids/*analysis, Aged ; Angioplasty, Balloon, Coronary/methods ; Coronary Angiography ; Drug-Eluting Stents ; Follow-Up Studies ; Humans ; Japan ; Male ; Middle Aged ; Predictive Value of Tests ; Prognosis ; Risk Factors ; Sirolimus ; Treatment Outcome ; Ultrasonography, Interventional/methods
مستخلص: We sought to determine the morphologic predictors of major adverse cardiac events (MACEs) after successful percutaneous coronary intervention (PCI) with drug-eluting stents (DES), using integrated backscatter intravascular ultrasound (IB-IVUS). Conventional IVUS and IB-IVUS were performed in 260 consecutive patients who underwent PCI with DES. Three-dimensional analyses were performed to determine plaque volume and the volume of each plaque component (lipid, fibrous, and calcification). Patients were divided into two groups according to the median lipid volume (LV) in the target lesion. MACEs were defined as death, nonfatal myocardial infarction, and any repeat revascularization. The median follow-up interval was 1285 days. MACEs were observed in 64 patients (24.6 %). Patients having a larger LV compared with their counterparts had worse long-term clinical outcomes regarding mortality (3.8 vs. 0 %, P = 0.02) and MACEs (31.5 vs. 17.7 %, P = 0.008) by log-rank test. After adjustment for confounders, large LV (odds ratio 1.95, 95 % confidence interval 1.14-3.33, P = 0.02) was significantly and independently associated with MACEs. The assessment of coronary plaque characteristics in the target lesion may be useful to predict long-term outcome following successful coronary intervention.
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المشرفين على المادة: 0 (Lipids)
W36ZG6FT64 (Sirolimus)
تواريخ الأحداث: Date Created: 20131022 Date Completed: 20150708 Latest Revision: 20211021
رمز التحديث: 20221213
DOI: 10.1007/s00380-013-0430-2
PMID: 24142068
قاعدة البيانات: MEDLINE
الوصف
تدمد:1615-2573
DOI:10.1007/s00380-013-0430-2