دورية أكاديمية
New cytotoxic spirostane saponin and biflavonoid glycoside from the leaves of Acacia saligna (Labill.) H.L. Wendl.
| العنوان: | New cytotoxic spirostane saponin and biflavonoid glycoside from the leaves of Acacia saligna (Labill.) H.L. Wendl. |
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| المؤلفون: | Gedara SR; a Department of Pharmacognosy, Faculty of Pharmacy , Mansoura University , Mansoura 35516 , Egypt., Galala AA |
| المصدر: | Natural product research [Nat Prod Res] 2014; Vol. 28 (5), pp. 324-9. Date of Electronic Publication: 2013 Dec 04. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Taylor & Francis Health Sciences Country of Publication: England NLM ID: 101167924 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1478-6427 (Electronic) Linking ISSN: 14786419 NLM ISO Abbreviation: Nat Prod Res Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: Milton Park, UK : Taylor & Francis Health Sciences, c2003- |
| مواضيع طبية MeSH: | Acacia/*chemistry , Biflavonoids/*isolation & purification , Biflavonoids/*pharmacology , Glycosides/*isolation & purification , Glycosides/*pharmacology , Saponins/*isolation & purification , Saponins/*pharmacology , Spirostans/*isolation & purification , Spirostans/*pharmacology, Biflavonoids/chemistry ; Drug Screening Assays, Antitumor ; Egypt ; Glycosides/chemistry ; Hep G2 Cells ; Humans ; Mannosides/chemistry ; Mannosides/isolation & purification ; Nuclear Magnetic Resonance, Biomolecular ; Plant Leaves/chemistry ; Saponins/chemistry ; Spirostans/chemistry |
| مستخلص: | New naturally occurring spirostane saponin (25S)-5β-spirostan-3β-yl-3-O-β-D-xylopyranosyl(1 → 3)-O-β-D-xylopyranosyl(1 → 4)-β-D-galactopyranoside (6) and biflavonoid glycoside myricetin-3-O-rhamnoside (C7-O-C7) myricetin-3-O-rhamnoside (4) along with a series of known compounds erythrodiol (1), 3β-O-trans-p-coumaroyl-erythrodiol (2), quercetin-3-O-α-L-rhamnoside (3) and myricetin-3-O-α-L-rhamnoside (5) were separated from the leaves of Acacia saligna (Labill.), H.L. Wendl. Compounds 1 and 2 were separated for the first time from genus Acacia. The structures of compounds 1-6 were established on the basis of extensive 1D and 2D NMR spectroscopic techniques in combination with EI-MS and HR-ESI-MS. These compounds were screened for their antioxidant and cytotoxic activities against HEPG2 (liver cancer) cell line and significant results were obtained. |
| المشرفين على المادة: | 0 ((25S)-5beta-spirostan-3beta-yl-3-O-beta-D-xylopyranosyl(1-3)-O--D-xylopyranosyl(1-4)-beta-D-galactopyranoside) 0 (Biflavonoids) 0 (Glycosides) 0 (Mannosides) 0 (Saponins) 0 (Spirostans) 0 (myricetin-3-O-rhamnoside) 0 (myricetin-3-O-rhamnoside (C7-O-C7) myricetin-3-O-rhamnoside) |
| تواريخ الأحداث: | Date Created: 20131206 Date Completed: 20140910 Latest Revision: 20220311 |
| رمز التحديث: | 20221213 |
| DOI: | 10.1080/14786419.2013.863200 |
| PMID: | 24304383 |
| قاعدة البيانات: | MEDLINE |
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Full Text Finder | تدمد: | 1478-6427 |
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| DOI: | 10.1080/14786419.2013.863200 |