دورية أكاديمية
Time for Option B+? Prevalence and characteristics of HIV infection among attendees of 2 antenatal clinics in Buea, Cameroon.
| العنوان: | Time for Option B+? Prevalence and characteristics of HIV infection among attendees of 2 antenatal clinics in Buea, Cameroon. |
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| المؤلفون: | Takow SE; Department of Clinical Sciences, Faculty of Health Sciences, University of Buea, Buea, Cameroon., Atashili J; Department of Clinical Sciences, Faculty of Health Sciences, University of Buea, Buea, Cameroon CANTAM HIV Research Laboratory, Faculty of Health Sciences, University of Buea, Buea, Cameroon atashili@yahoo.ie., Enow-Tanjong R; CANTAM HIV Research Laboratory, Faculty of Health Sciences, University of Buea, Buea, Cameroon., Mesembe MT; CANTAM HIV Research Laboratory, Faculty of Health Sciences, University of Buea, Buea, Cameroon., Ikomey GM; CANTAM HIV Research Laboratory, Faculty of Health Sciences, University of Buea, Buea, Cameroon., Ndip LM; Laboratory for Emerging Infectious Diseases, University of Buea, Buea, Cameroon., Mbuagbaw JC; Department of Clinical Sciences, Faculty of Health Sciences, University of Buea, Buea, Cameroon., Ndumbe PM; Department of Clinical Sciences, Faculty of Health Sciences, University of Buea, Buea, Cameroon CANTAM HIV Research Laboratory, Faculty of Health Sciences, University of Buea, Buea, Cameroon. |
| المصدر: | Journal of the International Association of Providers of AIDS Care [J Int Assoc Provid AIDS Care] 2015 Jan-Feb; Vol. 14 (1), pp. 77-81. Date of Electronic Publication: 2013 Dec 05. |
| نوع المنشور: | Journal Article; Research Support, Non-U.S. Gov't |
| اللغة: | English |
| بيانات الدورية: | Publisher: Sage Publications Country of Publication: United States NLM ID: 101603896 Publication Model: Print-Electronic Cited Medium: Print ISSN: 2325-9574 (Print) Linking ISSN: 23259574 NLM ISO Abbreviation: J Int Assoc Provid AIDS Care Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: Thousand Oaks, CA : Sage Publications, [2013]- |
| مواضيع طبية MeSH: | HIV Infections/*drug therapy , HIV Infections/*epidemiology , Pregnancy Complications, Infectious/*drug therapy , Pregnancy Complications, Infectious/*epidemiology, Adult ; Ambulatory Care Facilities ; Anti-Retroviral Agents/administration & dosage ; Anti-Retroviral Agents/therapeutic use ; CD4 Lymphocyte Count ; Cameroon/epidemiology ; Cross-Sectional Studies ; Female ; Humans ; Pregnancy ; Prenatal Care ; Prevalence ; Viral Load ; Young Adult |
| مستخلص: | As countries consider a wider use of triple antiretroviral therapy (ART) in pregnancy, which in recent World Health Organization guidelines is called Option B+, this study sought to explore the potential implications of adopting Option B+ by characterizing HIV infection in pregnant women attending 2 semiurban antenatal clinics in Cameroon. In a descriptive cross-sectional study, consenting women were screened for HIV; positive samples were confirmed using an enzyme-linked immunosorbent assay test, and CD4 levels and HIV viral loads were determined using flow cytometry and reverse transcription-polymerase chain reaction, respectively. The seroprevalence of HIV in the 407 pregnant women screened was 8.4% (95% confidence interval: 5.9%-11.5%). The majority (82.4%) of HIV-positive women had CD4 counts >350 cells/mm(3). A quarter (25%) had undetectable viral levels (<80 copies/mL). Adopting Option B+ in this setting would result in a 5-fold increase in the number of HIV-infected pregnant women being placed on lifelong triple ART. (© The Author(s) 2013.) |
| فهرسة مساهمة: | Keywords: CD4; Cameroon; HIV; pregnancy; viral load |
| المشرفين على المادة: | 0 (Anti-Retroviral Agents) |
| تواريخ الأحداث: | Date Created: 20131207 Date Completed: 20150331 Latest Revision: 20220311 |
| رمز التحديث: | 20240628 |
| DOI: | 10.1177/2325957413510607 |
| PMID: | 24309753 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 2325-9574 |
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| DOI: | 10.1177/2325957413510607 |