دورية أكاديمية
أعرض في EDS

Oral lesions among HIV-infected children on antiretroviral treatment in West Africa.

التفاصيل البيبلوغرافية
العنوان: Oral lesions among HIV-infected children on antiretroviral treatment in West Africa.
المؤلفون: Meless D; Programme PAC-CI/CHU de Treichville, Abidjan, Côte d'Ivoire.; Département de Santé Publique, UFR Odontostomatologie, Université FHB, Abidjan, Côte d'Ivoire., Ba B; CHU d'Odonto-Stomatologie, Bamako, Mali., Faye M; Hopital d'Enfants Albert Royer, Dakar, Sénégal., Diby JS; PMI Yopougon-Attié, Abidjan, Côte d'Ivoire., N'zoré S; CCTOS, Abidjan, Côte d'Ivoire., Datté S; CCTOS, Abidjan, Côte d'Ivoire., Diecket L; CHU de Yopougon, Abidjan, Côte d'Ivoire., N'Diaye C; Hôpital Gabriel Touré, Bamako, Mali., Aka EA; CePReF Enfant, Abidjan, Côte d'Ivoire., Kouakou K; CIRBA, Abidjan, Côte d'Ivoire., Ba A; Hopital d'Enfants Albert Royer, Dakar, Sénégal., Ekouévi DK; Programme PAC-CI/CHU de Treichville, Abidjan, Côte d'Ivoire.; Inserm U897, Equipe VIH et Santé Globale, Bordeaux, France., Dabis F; Inserm U897, Equipe VIH et Santé Globale, Bordeaux, France.; Université Bordeaux Segalen, Bordeaux, France., Shiboski C; University of California, San Francisco, CA, USA., Arrivé E; Inserm U897, Equipe VIH et Santé Globale, Bordeaux, France.; Université Bordeaux Segalen, Bordeaux, France.
المصدر: Tropical medicine & international health : TM & IH [Trop Med Int Health] 2014 Mar; Vol. 19 (3), pp. 246-255. Date of Electronic Publication: 2014 Jan 06.
نوع المنشور: Journal Article; Multicenter Study; Research Support, N.I.H., Extramural
اللغة: English
بيانات الدورية: Publisher: Blackwell Scientific Publications Country of Publication: England NLM ID: 9610576 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1365-3156 (Electronic) Linking ISSN: 13602276 NLM ISO Abbreviation: Trop Med Int Health Subsets: MEDLINE
أسماء مطبوعة: Publication: Oxford : Blackwell Scientific Publications
Original Publication: Oxford, UK : Blackwell Science Ltd, c1996-
مواضيع طبية MeSH: Anti-Retroviral Agents/*therapeutic use , Dental Caries/*epidemiology , HIV Infections/*epidemiology , Mouth Diseases/*epidemiology, Adolescent ; Africa, Western/epidemiology ; CD4 Lymphocyte Count ; Child ; Child, Preschool ; Confidence Intervals ; Cross-Sectional Studies ; Disease Progression ; Female ; HIV Infections/drug therapy ; HIV Infections/immunology ; Humans ; Logistic Models ; Male ; Mouth Diseases/pathology ; Mouth Diseases/virology ; Odds Ratio ; Oral Health/statistics & numerical data ; Oral Hygiene/statistics & numerical data ; Parotid Gland/pathology
مستخلص: Objective: To estimate the prevalence of oral mucosal diseases and dental caries among HIV-infected children receiving antiretroviral treatment (ART) in West Africa and to identify the factors associated with the prevalence of oral mucosal lesions.
Methods: Multicentre cross-sectional survey in five paediatric HIV clinics in Côte d'Ivoire, Mali and Sénégal. A standardised examination was performed by trained dentists on a random sample of HIV-infected children aged 5-15 years receiving ART. The prevalence of oral and dental lesions and mean number of decayed, missing/extracted and filled teeth (DMFdefT) in temporary and permanent dentition were estimated with their 95% confidence interval (95% CI). We used logistic regression to explore the association between children's characteristics and the prevalence of oral mucosal lesions, expressed as prevalence odds ratio (POR).
Results: The median age of the 420 children (47% females) enrolled was 10.4 years [interquartile range (IQR) = 8.3-12.6]. The median duration on ART was 4.6 years (IQR = 2.6-6.2); 84 (20.0%) had CD4 count<350 cells/mm(3). A total of 35 children (8.3%; 95% CI: 6.1-11.1) exhibited 42 oral mucosal lesions (24 were candidiasis); 86.0% (95% CI = 82.6-89.3) of children had DMFdefT ≥ 1. The presence of oral mucosal lesions was independently associated with CD4 count < 350 cells/mm(3) (POR = 2.96, 95% CI = 1.06-4.36) and poor oral hygiene (POR = 2.69, 95% CI = 1.07-6.76).
Conclusions: Oral mucosal lesions still occur in HIV-infected African children despite ART, but rarely. However, dental caries were common and severe in this population, reflecting the need to include oral health in the comprehensive care of HIV.
(© 2014 John Wiley & Sons Ltd.)
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معلومات مُعتمدة: U01 AI069919 United States AI NIAID NIH HHS; U01AI069919 United States AI NIAID NIH HHS
فهرسة مساهمة: Keywords: Africa; Côte d'Ivoire; HIV; Mali; Sénégal; antiretroviral therapy; child; oral health
المشرفين على المادة: 0 (Anti-Retroviral Agents)
تواريخ الأحداث: Date Created: 20140107 Date Completed: 20140414 Latest Revision: 20211021
رمز التحديث: 20221213
مُعرف محوري في PubMed: PMC4001247
DOI: 10.1111/tmi.12253
PMID: 24386972
قاعدة البيانات: MEDLINE
الوصف
تدمد:1365-3156
DOI:10.1111/tmi.12253