دورية أكاديمية
Flexible composition and execution of high performance, high fidelity multiscale biomedical simulations.
| العنوان: | Flexible composition and execution of high performance, high fidelity multiscale biomedical simulations. |
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| المؤلفون: | Groen D; Centre for Computational Science, University College London, UK., Borgdorff J; Section Computational Science, University of Amsterdam, The Netherlands., Bona-Casas C; Section Computational Science, University of Amsterdam, The Netherlands., Hetherington J; Centre for Computational Science, University College London, UK., Nash RW; Centre for Computational Science, University College London, UK., Zasada SJ; Centre for Computational Science, University College London, UK., Saverchenko I; Leibniz-Rechenzentrum, Garching, Germany., Mamonski M; Poznan Supercomputing and Networking Center, Poznan, Poland., Kurowski K; Poznan Supercomputing and Networking Center, Poznan, Poland., Bernabeu MO; Centre for Computational Science, University College London, UK., Hoekstra AG; Section Computational Science, University of Amsterdam, The Netherlands., Coveney PV; Centre for Computational Science, University College London, UK. |
| المصدر: | Interface focus [Interface Focus] 2013 Apr 06; Vol. 3 (2), pp. 20120087. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Royal Society Country of Publication: England NLM ID: 101531990 Publication Model: Print Cited Medium: Print ISSN: 2042-8898 (Print) Linking ISSN: 20428898 NLM ISO Abbreviation: Interface Focus Subsets: PubMed not MEDLINE |
| أسماء مطبوعة: | Original Publication: London : Royal Society, 2011- |
| مستخلص: | Multiscale simulations are essential in the biomedical domain to accurately model human physiology. We present a modular approach for designing, constructing and executing multiscale simulations on a wide range of resources, from laptops to petascale supercomputers, including combinations of these. Our work features two multiscale applications, in-stent restenosis and cerebrovascular bloodflow, which combine multiple existing single-scale applications to create a multiscale simulation. These applications can be efficiently coupled, deployed and executed on computers up to the largest (peta) scale, incurring a coupling overhead of 1-10% of the total execution time. |
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| معلومات مُعتمدة: | MR/K006584/1 United Kingdom MRC_ Medical Research Council |
| فهرسة مساهمة: | Keywords: blood flow; cerebrovascular bloodflow; distributed computing; high performance computing; in-stent restenosis; multiscale modelling |
| تواريخ الأحداث: | Date Created: 20140116 Date Completed: 20140115 Latest Revision: 20220129 |
| رمز التحديث: | 20231215 |
| مُعرف محوري في PubMed: | PMC3638484 |
| DOI: | 10.1098/rsfs.2012.0087 |
| PMID: | 24427530 |
| قاعدة البيانات: | MEDLINE |
| تدمد: | 2042-8898 |
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| DOI: | 10.1098/rsfs.2012.0087 |