دورية أكاديمية

Sero-prevalence of hepatitis B virus and hepatitis C virus among HIV patients in a suburban University Teaching Hospital in South-East Nigeria.

التفاصيل البيبلوغرافية
العنوان: Sero-prevalence of hepatitis B virus and hepatitis C virus among HIV patients in a suburban University Teaching Hospital in South-East Nigeria.
المؤلفون: Diwe CK; Department of Community Medicine, College of Medicine, Imo State University, Orlu Campus, Imo State, Nigeria., Okwara EC; Department of Chemical Pathology, Imo State University Teaching Hospital, Orlu, Imo State, Nigeria., Enwere OO; Department of Internal Medicine, College of Medicine, Imo State University, Orlu Campus, Imo State, Nigeria., Azike JE; Department of Surgery, College of Medicine, Imo State University, Orlu Campus, Imo State, Nigeria., Nwaimo NC; Department of Chemical Pathology, Imo State University Teaching Hospital, Orlu, Imo State, Nigeria.
المصدر: The Pan African medical journal [Pan Afr Med J] 2013 Sep 10; Vol. 16, pp. 7. Date of Electronic Publication: 2013 Sep 10 (Print Publication: 2013).
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: African Field Epidemiology Network Country of Publication: Uganda NLM ID: 101517926 Publication Model: eCollection Cited Medium: Internet ISSN: 1937-8688 (Electronic) NLM ISO Abbreviation: Pan Afr Med J Subsets: MEDLINE
أسماء مطبوعة: Original Publication: Kampala, Uganda : African Field Epidemiology Network
مواضيع طبية MeSH: HIV Infections/*epidemiology , Hepatitis B/*epidemiology , Hepatitis C/*epidemiology, Adult ; Coinfection ; Female ; HIV Infections/blood ; HIV Infections/complications ; Hepacivirus/immunology ; Hepatitis B/blood ; Hepatitis B/complications ; Hepatitis B virus/immunology ; Hepatitis C/blood ; Hepatitis C/complications ; Hospitals, Teaching ; Humans ; Male ; Middle Aged ; Nigeria/epidemiology ; Seroepidemiologic Studies
مستخلص: Introduction: Highly active antiretroviral therapy (HAART) has improved survival of human immunodeficiency virus (HIV) patients. Concurrent morbidities from liver diseases among these patients have also been observed due to co-infection with hepatitis B and C viruses (HBV and HCV). HAART reduces liver-associated morbidities and mortalities in such patients. Unfortunately free testing of HBV and HCV are not provided alongside free HIV testing and treatment in Nigeria. We assessed the seroprevalence of HBV and HCV among HIV patients presenting for treatment in our center.
Methods: This prospective study of adult patients with HIV/AIDS assessed the seroprevalence of HBV and HCV co-infection using a 19-item questionnaire and collection of 2ml venous blood for hepatitis B surface antigens (HBsAg) and anti-HCV antibodies. All previously diagnosed HIV patients of the unit were excluded from the study.
Results: Of the 404 patients, 69.2% were females while 30.8% were males. Married participants were 59.6%, 25.3% were single and 15% were previously married. A large proportion (69%) of patients were farmers, artisans and traders. Most had some formal education; secondary (55.3%), primary 27.3%, tertiary 13.8%. HBsAg positive participants were 9 (2.2%) while 3 (0.7%) were positive for HCV. No participant had triple infection of HIV/HBV/HCV.
Conclusion: Seroprevalence of HBV and HCV is low among HIV patients in Orlu. However there is a need for HBV and HCV testing of all HIV positive patients to reduce morbidities and mortalities from liver diseases.
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فهرسة مساهمة: Keywords: HBV; HCV; HIV; co-infection; liver disease; seroprevalence
تواريخ الأحداث: Date Created: 20140227 Date Completed: 20141118 Latest Revision: 20240413
رمز التحديث: 20240413
مُعرف محوري في PubMed: PMC3926757
DOI: 10.11604/pamj.2013.16.7.3077
PMID: 24570778
قاعدة البيانات: MEDLINE
الوصف
تدمد:1937-8688
DOI:10.11604/pamj.2013.16.7.3077