دورية أكاديمية
Long-term pretreatment with proton pump inhibitor and Helicobacter pylori eradication rates.
| العنوان: | Long-term pretreatment with proton pump inhibitor and Helicobacter pylori eradication rates. |
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| المؤلفون: | Yoon SB; Seung Bae Yoon, Jae Myung Park, Jong-Yul Lee, Myong Ki Baeg, Chul-Hyun Lim, Jin Soo Kim, Yu Kyung Cho, In Seok Lee, Sang Woo Kim, Myung-Gyu Choi, Division of Gastroenterology, Department of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul 137-856, South Korea., Park JM; Seung Bae Yoon, Jae Myung Park, Jong-Yul Lee, Myong Ki Baeg, Chul-Hyun Lim, Jin Soo Kim, Yu Kyung Cho, In Seok Lee, Sang Woo Kim, Myung-Gyu Choi, Division of Gastroenterology, Department of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul 137-856, South Korea., Lee JY; Seung Bae Yoon, Jae Myung Park, Jong-Yul Lee, Myong Ki Baeg, Chul-Hyun Lim, Jin Soo Kim, Yu Kyung Cho, In Seok Lee, Sang Woo Kim, Myung-Gyu Choi, Division of Gastroenterology, Department of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul 137-856, South Korea., Baeg MK; Seung Bae Yoon, Jae Myung Park, Jong-Yul Lee, Myong Ki Baeg, Chul-Hyun Lim, Jin Soo Kim, Yu Kyung Cho, In Seok Lee, Sang Woo Kim, Myung-Gyu Choi, Division of Gastroenterology, Department of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul 137-856, South Korea., Lim CH; Seung Bae Yoon, Jae Myung Park, Jong-Yul Lee, Myong Ki Baeg, Chul-Hyun Lim, Jin Soo Kim, Yu Kyung Cho, In Seok Lee, Sang Woo Kim, Myung-Gyu Choi, Division of Gastroenterology, Department of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul 137-856, South Korea., Kim JS; Seung Bae Yoon, Jae Myung Park, Jong-Yul Lee, Myong Ki Baeg, Chul-Hyun Lim, Jin Soo Kim, Yu Kyung Cho, In Seok Lee, Sang Woo Kim, Myung-Gyu Choi, Division of Gastroenterology, Department of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul 137-856, South Korea., Cho YK; Seung Bae Yoon, Jae Myung Park, Jong-Yul Lee, Myong Ki Baeg, Chul-Hyun Lim, Jin Soo Kim, Yu Kyung Cho, In Seok Lee, Sang Woo Kim, Myung-Gyu Choi, Division of Gastroenterology, Department of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul 137-856, South Korea., Lee IS; Seung Bae Yoon, Jae Myung Park, Jong-Yul Lee, Myong Ki Baeg, Chul-Hyun Lim, Jin Soo Kim, Yu Kyung Cho, In Seok Lee, Sang Woo Kim, Myung-Gyu Choi, Division of Gastroenterology, Department of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul 137-856, South Korea., Kim SW; Seung Bae Yoon, Jae Myung Park, Jong-Yul Lee, Myong Ki Baeg, Chul-Hyun Lim, Jin Soo Kim, Yu Kyung Cho, In Seok Lee, Sang Woo Kim, Myung-Gyu Choi, Division of Gastroenterology, Department of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul 137-856, South Korea., Choi MG; Seung Bae Yoon, Jae Myung Park, Jong-Yul Lee, Myong Ki Baeg, Chul-Hyun Lim, Jin Soo Kim, Yu Kyung Cho, In Seok Lee, Sang Woo Kim, Myung-Gyu Choi, Division of Gastroenterology, Department of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul 137-856, South Korea. |
| المصدر: | World journal of gastroenterology [World J Gastroenterol] 2014 Jan 28; Vol. 20 (4), pp. 1061-6. |
| نوع المنشور: | Journal Article; Research Support, Non-U.S. Gov't |
| اللغة: | English |
| بيانات الدورية: | Publisher: Baishideng Publishing Group Country of Publication: United States NLM ID: 100883448 Publication Model: Print Cited Medium: Internet ISSN: 2219-2840 (Electronic) Linking ISSN: 10079327 NLM ISO Abbreviation: World J Gastroenterol Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: 2014- : Pleasanton, CA : Baishideng Publishing Group Original Publication: Beijing : WJG Press, c1998- |
| مواضيع طبية MeSH: | Anti-Bacterial Agents/*administration & dosage , Helicobacter Infections/*drug therapy , Helicobacter pylori/*drug effects , Proton Pump Inhibitors/*administration & dosage, Adult ; Drug Administration Schedule ; Drug Therapy, Combination ; Female ; Helicobacter Infections/diagnosis ; Helicobacter Infections/microbiology ; Helicobacter pylori/pathogenicity ; Humans ; Male ; Middle Aged ; Retrospective Studies ; Time Factors ; Treatment Outcome |
| مستخلص: | Aim: To investigate whether proton pump inhibitor (PPI) pretreatment influences Helicobacter pylori eradication rate. Methods: We retrospectively reviewed H. pylori-infected patients who were treated with a standard triple regimen (PPI, amoxicillin 1 g, and clarithromycin 500 mg, all twice daily for 7 d). The diagnosis of H. pylori infection and its eradication was assessed with the rapid urease test, histological examination by silver staining, or the ¹³C-urea breath test. We divided the patients into two groups: one received the standard eradication regimen without PPI pretreatment (Group A), and the other received PPI pretreatment (Group B). The patients in Group B were reclassified into three groups based on the duration of PPI pretreatment: Group B-I (3-14 d), Group B-II (15-55 d), and Group B-III (≥ 56 d). Results: A total of 1090 patients were analyzed and the overall eradication rate was 80.9%. The cure rate in Group B (81.2%, 420/517) was not significantly different from that in Group A (79.2%, 454/573). The eradication rates in Group B-I, B-II and B-III were 80.1% (117/146), 81.8% (224/274) and 81.4% (79/97), respectively. Conclusion: PPI pretreatment did not affect H. pylori eradication rate, regardless of the medication period. |
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| فهرسة مساهمة: | Keywords: Antibiotics; Drug resistance; Helicobacter pylori; Proton pump inhibitor; Urea breath test |
| المشرفين على المادة: | 0 (Anti-Bacterial Agents) 0 (Proton Pump Inhibitors) |
| تواريخ الأحداث: | Date Created: 20140228 Date Completed: 20141117 Latest Revision: 20220408 |
| رمز التحديث: | 20240628 |
| مُعرف محوري في PubMed: | PMC3921530 |
| DOI: | 10.3748/wjg.v20.i4.1061 |
| PMID: | 24574779 |
| قاعدة البيانات: | MEDLINE |
| تدمد: | 2219-2840 |
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| DOI: | 10.3748/wjg.v20.i4.1061 |