Editorial & Opinion
Arguments in favor of HPV testing for cervical screening and post-treatment CIN2+ monitoring.
العنوان: | Arguments in favor of HPV testing for cervical screening and post-treatment CIN2+ monitoring. |
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المؤلفون: | Uijterwaal MH; Department of Pathology, VU University Medical Center, PO Box 7057, 1000 MB Amsterdam, The Netherlands., Verhoef VM, Snijders PJ, Meijer CJ |
المصدر: | Expert review of molecular diagnostics [Expert Rev Mol Diagn] 2014 Apr; Vol. 14 (3), pp. 245-8. Date of Electronic Publication: 2014 Mar 06. |
نوع المنشور: | Editorial |
اللغة: | English |
بيانات الدورية: | Publisher: Taylor & Francis Country of Publication: England NLM ID: 101120777 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1744-8352 (Electronic) Linking ISSN: 14737159 NLM ISO Abbreviation: Expert Rev Mol Diagn Subsets: MEDLINE |
أسماء مطبوعة: | Publication: 2015- : Abingdon, Oxford : Taylor & Francis Original Publication: London : Future Drugs Ltd, 2001- |
مواضيع طبية MeSH: | Human Papillomavirus DNA Tests/*methods , Uterine Cervical Neoplasms/*diagnosis, Aftercare ; Female ; Human Papillomavirus DNA Tests/economics ; Humans ; Prognosis ; Triage ; Uterine Cervical Neoplasms/therapy |
مستخلص: | Several studies have shown that the human papilloma virus (HPV) test is a more sensitive and objective primary cervical cancer screening tool than cytology. Therefore, conversion of cytology into HPV screening (as is planned in The Netherlands and some other European regions) will result in a better protection against cervical cancer and high-grade precursor lesions. Moreover, offering self-sampling for HPV testing will increase screening attendance by re-attracting former non-attendees. However, triage of HPV positive women is necessary because the specificity of HPV testing is 2-4% lower than of cytology. Several triage strategies have been evaluated, of which two, with cytology testing included, are feasible and were recently recommended. As an alternative for cytology triage, objective, non-morphological disease markers are upcoming and so far have shown promising results. Finally, HPV testing can also contribute to a more efficient monitoring of women treated for high-grade cervical precursor lesions, permitting fewer follow-up visits. |
تواريخ الأحداث: | Date Created: 20140307 Date Completed: 20141118 Latest Revision: 20140321 |
رمز التحديث: | 20221213 |
DOI: | 10.1586/14737159.2014.893829 |
PMID: | 24598044 |
قاعدة البيانات: | MEDLINE |
تدمد: | 1744-8352 |
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DOI: | 10.1586/14737159.2014.893829 |