دورية أكاديمية

Chronic Q fever in the Netherlands 5 years after the start of the Q fever epidemic: results from the Dutch chronic Q fever database.

التفاصيل البيبلوغرافية
العنوان: Chronic Q fever in the Netherlands 5 years after the start of the Q fever epidemic: results from the Dutch chronic Q fever database.
المؤلفون: Kampschreur LM; Division of Medicine, Department of Internal Medicine and Infectious Diseases, University Medical Centre Utrecht, Utrecht, the Netherlands., Delsing CE, Groenwold RH, Wegdam-Blans MC, Bleeker-Rovers CP, de Jager-Leclercq MG, Hoepelman AI, van Kasteren ME, Buijs J, Renders NH, Nabuurs-Franssen MH, Oosterheert JJ, Wever PC
المصدر: Journal of clinical microbiology [J Clin Microbiol] 2014 May; Vol. 52 (5), pp. 1637-43. Date of Electronic Publication: 2014 Mar 05.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: American Society for Microbiology Country of Publication: United States NLM ID: 7505564 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1098-660X (Electronic) Linking ISSN: 00951137 NLM ISO Abbreviation: J Clin Microbiol Subsets: MEDLINE
أسماء مطبوعة: Original Publication: Washington, American Society for Microbiology.
مواضيع طبية MeSH: Chronic Disease/*epidemiology , Q Fever/*epidemiology, Aged ; Cohort Studies ; Coxiella burnetii/isolation & purification ; Databases, Factual ; Disease Outbreaks ; Endocarditis/epidemiology ; Endocarditis/microbiology ; Epidemics ; Female ; Humans ; Male ; Middle Aged ; Netherlands/epidemiology ; Prevalence ; Q Fever/microbiology
مستخلص: Coxiella burnetii causes Q fever, a zoonosis, which has acute and chronic manifestations. From 2007 to 2010, the Netherlands experienced a large Q fever outbreak, which has offered a unique opportunity to analyze chronic Q fever cases. In an observational cohort study, baseline characteristics and clinical characteristics, as well as mortality, of patients with proven, probable, or possible chronic Q fever in the Netherlands, were analyzed. In total, 284 chronic Q fever patients were identified, of which 151 (53.7%) had proven, 64 (22.5%) probable, and 69 (24.3%) possible chronic Q fever. Among proven and probable chronic Q fever patients, vascular infection focus (56.7%) was more prevalent than endocarditis (34.9%). An acute Q fever episode was recalled by 27.0% of the patients. The all-cause mortality rate was 19.1%, while the chronic Q fever-related mortality rate was 13.0%, with mortality rates of 9.3% among endocarditis patients and 18% among patients with a vascular focus of infection. Increasing age (P=0.004 and 0.010), proven chronic Q fever (P=0.020 and 0.002), vascular chronic Q fever (P=0.024 and 0.005), acute presentation with chronic Q fever (P=0.002 and P<0.001), and surgical treatment of chronic Q fever (P=0.025 and P<0.001) were significantly associated with all-cause mortality and chronic Q fever-related mortality, respectively.
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تواريخ الأحداث: Date Created: 20140307 Date Completed: 20150224 Latest Revision: 20220316
رمز التحديث: 20231215
مُعرف محوري في PubMed: PMC3993626
DOI: 10.1128/JCM.03221-13
PMID: 24599987
قاعدة البيانات: MEDLINE
الوصف
تدمد:1098-660X
DOI:10.1128/JCM.03221-13