دورية أكاديمية

Do laser/LED phototherapies influence the outcome of the repair of surgical bone defects grafted with biphasic synthetic microgranular HA + β-tricalcium phosphate? A Raman spectroscopy study.

التفاصيل البيبلوغرافية
العنوان: Do laser/LED phototherapies influence the outcome of the repair of surgical bone defects grafted with biphasic synthetic microgranular HA + β-tricalcium phosphate? A Raman spectroscopy study.
المؤلفون: Soares LG; Center of Biophotonics, School of Dentistry, Federal University of Bahia, Av. Araújo Pinho, 62, Canela, Salvador, BA, 40110-150, Brazil., Marques AM, Aciole JM, da Guarda MG, Cangussú MC, Silveira L Jr, Pinheiro AL
المصدر: Lasers in medical science [Lasers Med Sci] 2014 Sep; Vol. 29 (5), pp. 1575-84. Date of Electronic Publication: 2014 Mar 14.
نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't
اللغة: English
بيانات الدورية: Publisher: Springer Country of Publication: England NLM ID: 8611515 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1435-604X (Electronic) Linking ISSN: 02688921 NLM ISO Abbreviation: Lasers Med Sci Subsets: MEDLINE
أسماء مطبوعة: Publication: London : Springer
Original Publication: London : Baillière Tindall, c1986-
مواضيع طبية MeSH: Biocompatible Materials*, Calcium Phosphates/*chemistry , Tibia/*radiation effects, Animals ; Bone Substitutes/chemistry ; Bone and Bones ; Lasers ; Light ; Low-Level Light Therapy ; Male ; Minerals ; Phototherapy ; Rats ; Rats, Wistar ; Spectrum Analysis, Raman ; Wound Healing
مستخلص: The treatment of bone loss is difficult. Many techniques are proposed to improve repair, including biomaterials and, recently, phototherapies. This work studied bone mineralization by Raman spectroscopy assessing intensities of Raman peaks of both inorganic (∼ 960, ∼ 1,070 cm(-1)) and organic (∼ 1,454 cm(-1)) contents in animal model. Six groups were studied: clot, laser, light-emitting diode (LED), biomaterial (HA + β-tricalcium phosphate), laser + biomaterial, and LED + biomaterial. Defects at right tibia were performed with a drill. When indicated, defects were further irradiated at a 48-h interval during 2 weeks. At the 15th and 30th days, the tibias were withdrawn and analyzed. The ∼ 960-cm(-1) peak was significantly affected by phototherapy on both clot- and biomaterial-filled defects. The ∼ 1,070-cm(-1) peak was affected by both time and the use of the LED light on clot-filled defects. On biomaterial-filled defects, only the use of the laser light significantly influenced the outcome. No significant influence of either the time or the use of the light was detected on clot-filled defects as regards the ∼ 1,454-cm(-1) peak. Raman intensities of both mineral and matrix components indicated that the use of laser and LED phototherapies improved the repair of bone defects grafted or not with biphasic synthetic microgranular HA + β-tricalcium phosphate.
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المشرفين على المادة: 0 (Biocompatible Materials)
0 (Bone Substitutes)
0 (Calcium Phosphates)
0 (Minerals)
0 (beta-tricalcium phosphate)
تواريخ الأحداث: Date Created: 20140315 Date Completed: 20151116 Latest Revision: 20211021
رمز التحديث: 20240628
DOI: 10.1007/s10103-014-1563-y
PMID: 24627284
قاعدة البيانات: MEDLINE
الوصف
تدمد:1435-604X
DOI:10.1007/s10103-014-1563-y