دورية أكاديمية
Myopia in asian subjects with primary angle closure: implications for glaucoma trends in East Asia.
| العنوان: | Myopia in asian subjects with primary angle closure: implications for glaucoma trends in East Asia. |
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| المؤلفون: | Yong KL; Singapore National Eye Centre and Singapore Eye Research Institute, Singapore, Republic of Singapore., Gong T; Bioinformatics Institute, A*STAR (Agency for Science, Technology and Research), Singapore, Republic of Singapore., Nongpiur ME; Singapore National Eye Centre and Singapore Eye Research Institute, Singapore, Republic of Singapore; Duke-NUS Graduate Medical School, Singapore, Republic of Singapore., How AC; Singapore National Eye Centre and Singapore Eye Research Institute, Singapore, Republic of Singapore., Lee HK; Bioinformatics Institute, A*STAR (Agency for Science, Technology and Research), Singapore, Republic of Singapore., Cheng L; Bioinformatics Institute, A*STAR (Agency for Science, Technology and Research), Singapore, Republic of Singapore., Perera SA; Singapore National Eye Centre and Singapore Eye Research Institute, Singapore, Republic of Singapore., Aung T; Singapore National Eye Centre and Singapore Eye Research Institute, Singapore, Republic of Singapore; Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Republic of Singapore. Electronic address: aung.tin@snec.com.sg. |
| المصدر: | Ophthalmology [Ophthalmology] 2014 Aug; Vol. 121 (8), pp. 1566-71. Date of Electronic Publication: 2014 Mar 25. |
| نوع المنشور: | Journal Article; Research Support, Non-U.S. Gov't |
| اللغة: | English |
| بيانات الدورية: | Publisher: Elsevier Country of Publication: United States NLM ID: 7802443 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1549-4713 (Electronic) Linking ISSN: 01616420 NLM ISO Abbreviation: Ophthalmology Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: 2000- : New York : Elsevier Original Publication: Rochester, Minn., American Academy of Ophthalmology. |
| مواضيع طبية MeSH: | Glaucoma, Angle-Closure/*epidemiology , Myopia/*epidemiology, Adult ; Aged ; Anterior Chamber/pathology ; Asian People/ethnology ; Axial Length, Eye/pathology ; Biometry ; Cross-Sectional Studies ; Female ; Glaucoma, Angle-Closure/classification ; Glaucoma, Angle-Closure/diagnosis ; Humans ; Intraocular Pressure ; Lens, Crystalline/pathology ; Male ; Middle Aged ; Myopia/diagnosis ; Prospective Studies ; Singapore/epidemiology ; Tomography, Optical Coherence ; Vitreous Body/pathology |
| مستخلص: | Purpose: To evaluate the occurrence of myopia in Asian subjects with angle closure and to assess the ocular biometric parameters in these subjects. Design: Cross-sectional study. Participants: We prospectively recruited 427 angle-closure subjects (143 primary angle-closure suspects, 75 patients with primary angle closure, 165 patients with primary angle-closure glaucoma, and 44 patients with acute primary angle closure) from a Singapore hospital. Methods: Refractive status was derived from the spherical equivalent of autorefraction. A-scan biometry (Nidek Echoscan Ultrasound US-800; Nidek Co., Tokyo, Japan) was performed to obtain anterior chamber depth (ACD), axial length (AL), lens thickness, and vitreous cavity length (VL). Anterior segment optical coherence tomography was performed to measure lens vault. Main Outcome Measures: Refractive status was categorized as myopia (≤-0.50 diopter [D]), emmetropia (-0.50 to +0.50 D), and hyperopia (≥+0.50 D). Results: The mean age ± standard deviation of study subjects was 65.6 ± 7.6 years, with most being Chinese (n = 394; 92.3%) and women (n = 275; 64.4%). Overall, myopia was present in 94 subjects (22%), hyperopia was present in 222 subjects (52%), and emmetropia was present in 111 subjects (26%). Of the 94 myopic angle-closure patients, 28 (29.8%) were categorized as having moderate myopia (≤-2.0 to -5.0 D) and 11 (11.7%) were categorized as having high myopia (≤-5.00 D). Although myopic angle-closure subjects had longer ALs (P<0.001) and VLs (P = 0.001) than their emmetropic and hyperopic counterparts, there were no significant differences in ACD (P = 0.77), lens thickness (P = 0.44), or lens vault (P = 0.053). Conclusions: Almost one quarter of angle-closure patients were myopic. Myopic angle-closure subjects had longer VLs and ALs, but there was no difference in ACD. With the increasing rate of myopia in many East Asian populations, there may be many subjects with axial myopia but shallow ACD and angle closure. The implication is that ophthalmologists should not assume that glaucoma patients who are myopic have open angles. (Copyright © 2014 American Academy of Ophthalmology. Published by Elsevier Inc. All rights reserved.) |
| تواريخ الأحداث: | Date Created: 20140401 Date Completed: 20141204 Latest Revision: 20221207 |
| رمز التحديث: | 20231215 |
| DOI: | 10.1016/j.ophtha.2014.02.006 |
| PMID: | 24679835 |
| قاعدة البيانات: | MEDLINE |
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Full Text Finder | تدمد: | 1549-4713 |
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| DOI: | 10.1016/j.ophtha.2014.02.006 |