دورية أكاديمية
Outcomes in renal transplant recipients with lupus nephritis: experience at a single center.
| العنوان: | Outcomes in renal transplant recipients with lupus nephritis: experience at a single center. |
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| المؤلفون: | Wagner CS; Santa Casa of Sao Paulo School of Medical Sciences , Sao Paulo, SP , Brazil., Malafronte P, Demetrio DP, de Souza JF, Sens YA |
| المصدر: | Renal failure [Ren Fail] 2014 Jul; Vol. 36 (6), pp. 912-5. Date of Electronic Publication: 2014 May 06. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Informa Healthcare Country of Publication: England NLM ID: 8701128 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1525-6049 (Electronic) Linking ISSN: 0886022X NLM ISO Abbreviation: Ren Fail Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: London : Informa Healthcare Original Publication: New York, N.Y. : M. Dekker, c1987- |
| مواضيع طبية MeSH: | Kidney Transplantation*, Lupus Nephritis/*surgery, Female ; Humans ; Male ; Retrospective Studies ; Treatment Outcome ; Young Adult |
| مستخلص: | Background: The long-term prognosis of renal transplant recipients with systemic lupus erythematosus is still controversial. The outcome of these patients depends on the population studied, race/ethnicity, socioeconomic conditions, donor-related factors and recurrent lupus nephritis (LN), among other factors. Objective: This study was conducted to evaluate kidney transplantation outcomes for adult Brazilian patients with LN at a single center. Subjects and Method: The archival records of all patients with LN who had received a kidney transplant at Santa Casa of Sao Paulo Hospítal were reviewed. Kaplan-Meier method was used to determine the survival rate. Results: We identified 18 patients with LN subjected to 22 kidney transplants during the 20-year interval. Two patients received three renal grafts. The majority of the patients were female, with 33.7 ± 10 years at the time of the transplantation, and half of them were African descendants or mixed. Sixteen transplants were performed from deceased donors and six from living-related donors. The patient survival rate was 90%, and graft survival was 68% at 10 years. Chronic allograft nephropathy was the major cause of graft loss. Two patients developed extra-renal manifestations of lupus. There was no clinical or histological evidence of recurrent LN. Conclusion: Renal transplantation is a method which can provide a long-term survival for patients with SLE and end-stage renal disease. |
| فهرسة مساهمة: | Keywords: Lupus nephritis; outcome; renal transplantation; survival; systemic lupus erythematosus |
| تواريخ الأحداث: | Date Created: 20140507 Date Completed: 20150330 Latest Revision: 20140625 |
| رمز التحديث: | 20221213 |
| DOI: | 10.3109/0886022X.2014.915196 |
| PMID: | 24798067 |
| قاعدة البيانات: | MEDLINE |
PDF full text from Publisher | تدمد: | 1525-6049 |
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| DOI: | 10.3109/0886022X.2014.915196 |