دورية أكاديمية
Dual-energy CT pulmonary angiography in patients with suspected pulmonary embolism: value for the detection and quantification of pulmonary venous congestion.
| العنوان: | Dual-energy CT pulmonary angiography in patients with suspected pulmonary embolism: value for the detection and quantification of pulmonary venous congestion. |
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| المؤلفون: | Thieme SF; Institute for Clinical Radiology, Ludwig-Maximilians-University Hospital Munich, Munich, Germany., Meinel FG, Graef A, Helck AD, Reiser MF, Johnson TR |
| المصدر: | The British journal of radiology [Br J Radiol] 2014 Jul; Vol. 87 (1039), pp. 20140079. Date of Electronic Publication: 2014 May 14. |
| نوع المنشور: | Journal Article; Research Support, Non-U.S. Gov't |
| اللغة: | English |
| بيانات الدورية: | Publisher: Oxford University Press Country of Publication: England NLM ID: 0373125 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1748-880X (Electronic) Linking ISSN: 00071285 NLM ISO Abbreviation: Br J Radiol Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: January 2024- : [Oxford] : Oxford University Press Original Publication: London, British Institute of Radiology. |
| مواضيع طبية MeSH: | Pulmonary Circulation*, Angiography/*methods , Heart Failure/*diagnosis , Hyperemia/*diagnostic imaging , Pulmonary Embolism/*diagnostic imaging , Tomography, X-Ray Computed/*methods, Adolescent ; Adult ; Aged ; Aged, 80 and over ; Female ; Heart Failure/diagnostic imaging ; Heart Failure/physiopathology ; Humans ; Image Processing, Computer-Assisted ; Male ; Middle Aged ; Pulmonary Artery/diagnostic imaging ; Pulmonary Embolism/physiopathology ; ROC Curve ; Reproducibility of Results ; Retrospective Studies ; Sensitivity and Specificity ; Young Adult |
| مستخلص: | Objective: To evaluate if vascular and pulmonary parenchymal enhancement values in dual-energy (DE) CT pulmonary angiography (CTPA) can suggest the diagnosis of pulmonary congestion. Methods: DE-CTPA images of 90 out of 1321 patients negative for pulmonary embolism showed signs of congestive heart failure. We measured DE-derived pulmonary parenchymal [perfused blood volume (PBV)], pulmonary artery (PA) and left atrium (LA) enhancement values in these patients and in 142 control patients. Enhancement values were compared between the populations and correlated with serum values of B-type natriuretic peptide (BNP) and proBNP, where available. Results: No significant difference of PBV but significant differences of mean PA and LA enhancement and individual enhancement differences (PA - LA) were found between the populations. PA - LA was higher in patients with elevated BNP and proBNP and was positively correlated with these values. Receiver operating characteristic analysis revealed a moderate discriminatory power of the PA - LA difference for the presence of cardiac biomarker elevations. Conclusion: PBV in DE-CTPA is not altered in patients with signs of congestive heart failure. However, differences in enhancement values in the pre- and post-pulmonary vessels were found in comparison with the control population. Advances in Knowledge: Altered pulmonary vascular haemodynamics in pulmonary venous congestion are not reflected in dual-energy-derived PBV maps. In the diagnosis of left heart failure in patients with chest pain and dyspnoea, density measurements in the pulmonary artery and in the left atrium in CTPA images may be a helpful diagnostic tool. |
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| تواريخ الأحداث: | Date Created: 20140516 Date Completed: 20141209 Latest Revision: 20211021 |
| رمز التحديث: | 20231215 |
| مُعرف محوري في PubMed: | PMC4075589 |
| DOI: | 10.1259/bjr.20140079 |
| PMID: | 24827378 |
| قاعدة البيانات: | MEDLINE |
| تدمد: | 1748-880X |
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| DOI: | 10.1259/bjr.20140079 |