دورية أكاديمية

Tattoo-associated uveitis.

التفاصيل البيبلوغرافية
العنوان: Tattoo-associated uveitis.
المؤلفون: Ostheimer TA; Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, Maryland. Electronic address: tosthei1@jhmi.edu., Burkholder BM; Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, Maryland., Leung TG; Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, Maryland., Butler NJ; Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, Maryland., Dunn JP; Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, Maryland., Thorne JE; Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, Maryland; Department of Epidemiology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland.
المصدر: American journal of ophthalmology [Am J Ophthalmol] 2014 Sep; Vol. 158 (3), pp. 637-43.e1. Date of Electronic Publication: 2014 May 27.
نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
اللغة: English
بيانات الدورية: Publisher: Elsevier Science Country of Publication: United States NLM ID: 0370500 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-1891 (Electronic) Linking ISSN: 00029394 NLM ISO Abbreviation: Am J Ophthalmol Subsets: MEDLINE
أسماء مطبوعة: Publication: 1999- : New York, NY : Elsevier Science
Original Publication: [Chicago, etc., Ophthalmic Pub. Co., etc.]
مواضيع طبية MeSH: Fluocinolone Acetonide/*therapeutic use , Tattooing/*adverse effects , Uveitis, Anterior/*etiology, Adult ; Biopsy ; Female ; Follow-Up Studies ; Glucocorticoids/therapeutic use ; Humans ; Male ; Prognosis ; Recurrence ; Retrospective Studies ; Skin/drug effects ; Skin/pathology ; Uveitis, Anterior/diagnosis ; Uveitis, Anterior/drug therapy ; Visual Acuity ; Young Adult
مستخلص: Purpose: To describe the clinical presentation of uveitis with coincident onset of raised and indurated tattooed skin.
Design: Case series.
Methods: Seven consecutive patients were evaluated at a tertiary ophthalmologic facility with coincident uveitis and cutaneous tattoo induration over an 18-month period. All subjects underwent complete ophthalmic examination and a focused systemic medical evaluation including serologic testing and imaging studies. Two participants underwent biopsy of their tattoos. The patients' clinical courses and responses to treatment over a follow-up period of 1-20 months are reported (mean follow-up = 9 months). Main outcome measures included degree of intraocular inflammation, ocular complications, visual acuity, clinically observable tattooed skin changes, and biopsy results.
Results: Five of 7 patients had bilateral nongranulomatous anterior uveitis: 4 with chronic and 1 with recurrent disease. The remaining 2 patients had bilateral chronic granulomatous panuveitis. Biopsies of raised and indurated tattoos were performed in 2 patients and demonstrated noncaseating granulomatous inflammation surrounding tattoo ink in the dermis. The skin changes resolved in all patients, with a faster response noted in those treated with high-dose oral prednisone for intraocular inflammation. Five patients subsequently experienced recurrent flares of intraocular inflammation in conjunction with the recurrence of raised and indurated tattoos.
Conclusions: These cases represent a subset of patients in whom skin tattooing may have incited an immune response leading to simultaneous inflammation of the eyes and tattooed skin.
(Copyright © 2014 Elsevier Inc. All rights reserved.)
التعليقات: Comment in: Am J Ophthalmol. 2014 Dec;158(6):1355-6. (PMID: 25457706)
Comment in: Am J Ophthalmol. 2014 Dec;158(6):1356. (PMID: 25457708)
Comment in: Am J Ophthalmol. 2015 Feb;159(2):409-10. (PMID: 25476724)
Comment in: Am J Ophthalmol. 2015 Feb;159(2):408-9. (PMID: 25542561)
المشرفين على المادة: 0 (Glucocorticoids)
0CD5FD6S2M (Fluocinolone Acetonide)
تواريخ الأحداث: Date Created: 20140531 Date Completed: 20141104 Latest Revision: 20220331
رمز التحديث: 20221213
DOI: 10.1016/j.ajo.2014.05.019
PMID: 24875002
قاعدة البيانات: MEDLINE
الوصف
تدمد:1879-1891
DOI:10.1016/j.ajo.2014.05.019