دورية أكاديمية
Magnetic resonance direct thrombus imaging differentiates acute recurrent ipsilateral deep vein thrombosis from residual thrombosis.
| العنوان: | Magnetic resonance direct thrombus imaging differentiates acute recurrent ipsilateral deep vein thrombosis from residual thrombosis. |
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| المؤلفون: | Tan M; Department of Thrombosis and Hemostasis, Leiden University Medical Center, Leiden, The Netherlands;, Mol GC; Department of Internal Medicine, Diakonessenhuis, Utrecht, The Netherlands;, van Rooden CJ; Department of Radiology, Haga Teaching Hospital, The Hague, The Netherlands;, Klok FA; Department of Thrombosis and Hemostasis, Leiden University Medical Center, Leiden, The Netherlands;, Westerbeek RE; Department of Radiology, Deventer Hospital, Deventer, The Netherlands;, Iglesias Del Sol A; Department of Internal Medicine, Rijnland Hospital, Leiderdorp, The Netherlands; and., van de Ree MA; Department of Internal Medicine, Diakonessenhuis, Utrecht, The Netherlands;, de Roos A; Department of Radiology, Leiden University Medical Center, Leiden, The Netherlands., Huisman MV; Department of Thrombosis and Hemostasis, Leiden University Medical Center, Leiden, The Netherlands; |
| المصدر: | Blood [Blood] 2014 Jul 24; Vol. 124 (4), pp. 623-7. Date of Electronic Publication: 2014 Jun 13. |
| نوع المنشور: | Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't |
| اللغة: | English |
| بيانات الدورية: | Publisher: Elsevier Country of Publication: United States NLM ID: 7603509 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1528-0020 (Electronic) Linking ISSN: 00064971 NLM ISO Abbreviation: Blood Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: 2021- : [New York] : Elsevier Original Publication: New York, Grune & Stratton [etc.] |
| مواضيع طبية MeSH: | Leg/*blood supply , Magnetic Resonance Imaging/*methods , Thrombosis/*classification , Thrombosis/*pathology , Veins/*pathology, Adolescent ; Adult ; Aged ; Female ; Humans ; Male ; Middle Aged ; Prognosis ; Prospective Studies ; Recurrence ; Young Adult |
| مستخلص: | Accurate diagnostic assessment of suspected ipsilateral recurrent deep vein thrombosis (DVT) is a major clinical challenge because differentiating between acute recurrent thrombosis and residual thrombosis is difficult with compression ultrasonography (CUS). We evaluated noninvasive magnetic resonance direct thrombus imaging (MRDTI) in a prospective study of 39 patients with symptomatic recurrent ipsilateral DVT (incompressibility of a different proximal venous segment than at the prior DVT) and 42 asymptomatic patients with at least 6-month-old chronic residual thrombi and normal D-dimer levels. All patients were subjected to MRDTI. MRDTI images were judged by 2 independent radiologists blinded for the presence of acute DVT and a third in case of disagreement. The sensitivity, specificity, and interobserver reliability of MRDTI were determined. MRDTI demonstrated acute recurrent ipsilateral DVT in 37 of 39 patients and was normal in all 42 patients without symptomatic recurrent disease for a sensitivity of 95% (95% CI, 83% to 99%) and a specificity of 100% (95% CI, 92% to 100%). Interobserver agreement was excellent (κ = 0.98). MRDTI images were adequate for interpretation in 95% of the cases. MRDTI is a sensitive and reproducible method for distinguishing acute ipsilateral recurrent DVT from 6-month-old chronic residual thrombi in the leg veins. (© 2014 by The American Society of Hematology.) |
| تواريخ الأحداث: | Date Created: 20140615 Date Completed: 20141118 Latest Revision: 20210202 |
| رمز التحديث: | 20240628 |
| DOI: | 10.1182/blood-2014-04-566380 |
| PMID: | 24928859 |
| قاعدة البيانات: | MEDLINE |
| تدمد: | 1528-0020 |
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| DOI: | 10.1182/blood-2014-04-566380 |