دورية أكاديمية
Stroke incidence and risk factors in Havana and Matanzas, Cuba.
العنوان: | Stroke incidence and risk factors in Havana and Matanzas, Cuba. |
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المؤلفون: | Llibre-Guerra JC; Departamento de Neurología, Unidad de Ictus, Instituto de Neurología y Neurocirugía, Universidad Médica de La Habana, La Habana, Cuba. Electronic address: pereraelianne@infomedsld.cu., Valhuerdi Cepero A; Servicio de Medicina Interna, Hospital Universitario Faustino Pérez, Matanzas, Cuba., Fernández Concepción O; Departamento de Neurología, Unidad de Ictus, Instituto de Neurología y Neurocirugía, Universidad Médica de La Habana, La Habana, Cuba., Llibre-Guerra JJ; Departamento de Neurología, Unidad de Ictus, Instituto de Neurología y Neurocirugía, Universidad Médica de La Habana, La Habana, Cuba., Gutiérrez RF; Centro de Estudios de Alzheimer, Universidad Médica de La Habana, La Habana, Cuba., Llibre-Rodriguez JJ; Departamento de Medicina Familiar, AC Universidad Autónoma de Nuevo León, Monterrey, México. |
المصدر: | Neurologia (Barcelona, Spain) [Neurologia] 2015 Oct; Vol. 30 (8), pp. 488-95. Date of Electronic Publication: 2014 Jun 18. |
نوع المنشور: | Journal Article |
اللغة: | English; Spanish; Castilian |
بيانات الدورية: | Publisher: Elsevier Doyma Country of Publication: Spain NLM ID: 9005460 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1578-1968 (Electronic) Linking ISSN: 02134853 NLM ISO Abbreviation: Neurologia Subsets: MEDLINE |
أسماء مطبوعة: | Publication: <2010- > : Barcelona : Elsevier Doyma Original Publication: [Barcelona] : Sociedad Española de Neurología |
مواضيع طبية MeSH: | Stroke/*epidemiology, Aged ; Aged, 80 and over ; Cuba/epidemiology ; Female ; Humans ; Incidence ; Interviews as Topic ; Male ; Proportional Hazards Models ; Prospective Studies ; Risk Factors ; Sex Factors |
مستخلص: | Introduction: Cerebrovascular disease is the third-leading cause of death and the second-leading cause of disability and dementia. Objective: Determine stroke incidence and risk factors in a population of adults aged 65 and over in Cuba (Havana and Matanzas). Material and Methods: This prospective longitudinal study, completed between April 2008 and Abril 2011, re-evaluated 2916 elderly adults with an average follow-up time of 4 years. Cases included 2316 living subjects and 600 verbal autopsies. Study variables were age, sex, educational level, self-reported health, and description of chronic diseases and substance abuse. Laboratory tests included genotyping APOE. Stroke was diagnosed based on the World Health Organization definition. We calculated the global incidence rate for stroke, broken down by sex, age group, and risk factors for incident stroke. Results: Stroke incidence was 786.2 in 100000 persons/year (95% CI: 672.3-906.4). History of alcohol consumption (HR: 3.5; 95% CI: 3.3-3.7), dementia (HR: 3.0; 95% CI, 1.6-5.5) and male sex (HR: 1.8; 95% CI, 1.2-2.8) were shown to be risk factors for incident stroke. Conclusions: Stroke incidence was similar to rates reported in developed countries and lower than that in low- to middle-income countries. Given that diabetes mellitus, heart disease, arterial hypertension, smoking, APOE4, etc. are associated with higher mortality rates, they will require separate analysis in a study of stroke risk factors. (Copyright © 2014 Sociedad Española de Neurología. Published by Elsevier España, S.L.U. All rights reserved.) |
فهرسة مساهمة: | Keywords: Apolipoprotein E4; Apolipoproteína E4; Factores de riesgo; Ictus; Incidence; Incidencia; Risk factors; Stroke |
تواريخ الأحداث: | Date Created: 20140622 Date Completed: 20160602 Latest Revision: 20150928 |
رمز التحديث: | 20240628 |
DOI: | 10.1016/j.nrl.2014.04.004 |
PMID: | 24950858 |
قاعدة البيانات: | MEDLINE |
تدمد: | 1578-1968 |
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DOI: | 10.1016/j.nrl.2014.04.004 |