دورية أكاديمية

Factors influencing herpes simplex virus type 2 infection among females in Enugu, Enugu State, Nigeria.

التفاصيل البيبلوغرافية
العنوان: Factors influencing herpes simplex virus type 2 infection among females in Enugu, Enugu State, Nigeria.
المؤلفون: Ojinmah UR, Ozoh GA, Onyekonwu CL
المصدر: Nigerian journal of medicine : journal of the National Association of Resident Doctors of Nigeria [Niger J Med] 2014 Apr-Jun; Vol. 23 (2), pp. 130-41.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: The Association Country of Publication: Nigeria NLM ID: 100888321 Publication Model: Print Cited Medium: Print ISSN: 1115-2613 (Print) Linking ISSN: 11152613 NLM ISO Abbreviation: Niger J Med Subsets: MEDLINE
أسماء مطبوعة: Original Publication: [Lagos, Nigeria] : The Association,
مواضيع طبية MeSH: Coinfection/*epidemiology , HIV Infections/*epidemiology , Herpes Genitalis/*epidemiology , Herpesvirus 2, Human/*isolation & purification, Adult ; Aged ; Antibodies, Viral/blood ; Coinfection/transmission ; Coinfection/virology ; Demography ; Female ; HIV Infections/complications ; HIV Infections/transmission ; Herpes Genitalis/complications ; Herpes Genitalis/transmission ; Humans ; Mass Screening ; Middle Aged ; Nigeria/epidemiology ; Prevalence ; Risk Factors ; Sexual Partners ; Surveys and Questionnaires
مستخلص: Background: Herpes Simplex Virus infection is a chronic infection of the sensory ganglia with variable levels of epithelial expression. An important feature of HSV infection is the recurrence of disease as a result of periodic or sporadic activation of viral replication. In addition, asymptomatic shedding of herpes viruses may play a significant role in transmission from person to person. This infection being lifelong manifests only in a small proportion of those infected. It has presented public health concern because of its progressively increasing prevalence which some reports say is of epidemic proportion in developing countries and also for its synergistic effect with HIV infection.
Objectives: Determination of antibody prevalence to HSV-2/co-infection with HIV among females attending skin and ANC clinics in UNTH and ESUTH.
Materials and Methods: One hundred and eighty suitably qualified subjects were appropriately recruited over a period of six months into this study. Essential information was collected using a questionnaire. Venous blood was also obtained for HSV 2 serology, HIV screening, and confirmation, if positive.
Results: The antibody prevalence of HSV 2 was found to be 77.8% (n = 137) and 14.6% (n = 20) had clinical diagnosis. The HIV and HSV-2 co-infection rate was 5.11% (n = 9). The risk factors for groups 1 [HSV2 Infection] and 2 [HSV2 & HIV co-infection] were similar with few differences, thus buttressing the fact that their modes of transmission are similar.
Conclusion: Factors influencing Herpes simplex virus type 2 infection among females in Enugu included among other things older age and increasing number of lifetime sexual partners.
المشرفين على المادة: 0 (Antibodies, Viral)
تواريخ الأحداث: Date Created: 20140625 Date Completed: 20140710 Latest Revision: 20151119
رمز التحديث: 20221213
PMID: 24956686
قاعدة البيانات: MEDLINE