دورية أكاديمية
أعرض في EDS

Serum lipids, apolipoproteins, and mortality among coronary artery disease patients.

التفاصيل البيبلوغرافية
العنوان: Serum lipids, apolipoproteins, and mortality among coronary artery disease patients.
المؤلفون: Ding D; Guangdong Provincial Key Laboratory of Food, Nutrition and Health, Department of Nutrition, School of Public Health, Sun Yat-sen University, No. 74 Zhongshan Road 2, Guangzhou, Guangdong 510080, China ; Chronic Disease Epidemiology Laboratory, Pennington Biomedical Research Center, 6400 Perkins Road, Baton Rouge, LA 70808, USA., Li X; Guangdong Provincial Key Laboratory of Food, Nutrition and Health, Department of Nutrition, School of Public Health, Sun Yat-sen University, No. 74 Zhongshan Road 2, Guangzhou, Guangdong 510080, China., Qiu J; Department of Cardiology, General Hospital of Guangzhou Military Command of People's Liberation Army, Guangdong 510010, China., Li R; Department of Cardiology, General Hospital of Guangzhou Military Command of People's Liberation Army, Guangdong 510010, China., Zhang Y; Department of Cardiology, General Hospital of Guangzhou Military Command of People's Liberation Army, Guangdong 510010, China., Su D; Guangdong Provincial Key Laboratory of Food, Nutrition and Health, Department of Nutrition, School of Public Health, Sun Yat-sen University, No. 74 Zhongshan Road 2, Guangzhou, Guangdong 510080, China., Li Z; Guangdong Provincial Key Laboratory of Food, Nutrition and Health, Department of Nutrition, School of Public Health, Sun Yat-sen University, No. 74 Zhongshan Road 2, Guangzhou, Guangdong 510080, China., Wang M; Guangdong Provincial Key Laboratory of Food, Nutrition and Health, Department of Nutrition, School of Public Health, Sun Yat-sen University, No. 74 Zhongshan Road 2, Guangzhou, Guangdong 510080, China., Lv X; Guangdong Provincial Key Laboratory of Food, Nutrition and Health, Department of Nutrition, School of Public Health, Sun Yat-sen University, No. 74 Zhongshan Road 2, Guangzhou, Guangdong 510080, China., Wang D; Guangdong Provincial Key Laboratory of Food, Nutrition and Health, Department of Nutrition, School of Public Health, Sun Yat-sen University, No. 74 Zhongshan Road 2, Guangzhou, Guangdong 510080, China., Yang Y; Guangdong Provincial Key Laboratory of Food, Nutrition and Health, Department of Nutrition, School of Public Health, Sun Yat-sen University, No. 74 Zhongshan Road 2, Guangzhou, Guangdong 510080, China., Xia M; Guangdong Provincial Key Laboratory of Food, Nutrition and Health, Department of Nutrition, School of Public Health, Sun Yat-sen University, No. 74 Zhongshan Road 2, Guangzhou, Guangdong 510080, China., Li D; Guangdong Provincial Key Laboratory of Food, Nutrition and Health, Department of Nutrition, School of Public Health, Sun Yat-sen University, No. 74 Zhongshan Road 2, Guangzhou, Guangdong 510080, China., Hu G; Chronic Disease Epidemiology Laboratory, Pennington Biomedical Research Center, 6400 Perkins Road, Baton Rouge, LA 70808, USA., Ling W; Guangdong Provincial Key Laboratory of Food, Nutrition and Health, Department of Nutrition, School of Public Health, Sun Yat-sen University, No. 74 Zhongshan Road 2, Guangzhou, Guangdong 510080, China.
المصدر: BioMed research international [Biomed Res Int] 2014; Vol. 2014, pp. 709756. Date of Electronic Publication: 2014 May 29.
نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't
اللغة: English
بيانات الدورية: Publisher: Hindawi Pub. Co Country of Publication: United States NLM ID: 101600173 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2314-6141 (Electronic) NLM ISO Abbreviation: Biomed Res Int Subsets: MEDLINE
أسماء مطبوعة: Original Publication: New York, NY : Hindawi Pub. Co.
مواضيع طبية MeSH: Apolipoproteins/*blood , Coronary Artery Disease/*blood , Coronary Artery Disease/*mortality, Adult ; Aged ; Aged, 80 and over ; Apolipoprotein A-I/blood ; Apolipoproteins B/blood ; China/epidemiology ; Cholesterol, HDL/blood ; Cholesterol, LDL/blood ; Female ; Humans ; Male ; Middle Aged ; Proportional Hazards Models ; Treatment Outcome
مستخلص: The proatherogenic effect of low-density lipoprotein cholesterol (LDL-C) and antiatherogenic effect of high-density lipoprotein cholesterol (HDL-C) have been confirmed in general population. But controversy arises among coronary artery disease (CAD) patients. The goal of this study was to identify the association of different lipid measurements with CAD prognosis. The study cohort included 1916 CAD patients who were 40-85 years of age. Cox proportional hazards regression models were used to estimate the association of baseline 6 lipid factors and 3 ratios with all-cause and cardiovascular (CVD) mortality. During a median follow-up of 3.1 years, 147 deaths were recorded, 113 of which were due to CVD. When lipid factors were categorized, HDL-C showed a U-shape association with all-cause and CVD mortality after adjustment for major CVD risk factors. Serum LDL-C, apoB, LDL/HDL ratio, and apoB/apoA-I ratio were positively, and apoA-I level was inversely associated with the risk of CVD mortality. After further pairwise comparison of lipid-related risk, LDL/HDL ratio and LDL-C had stronger association with all-cause and CVD mortality than other proatherogenic measurements among Chinese CAD patients.
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المشرفين على المادة: 0 (Apolipoprotein A-I)
0 (Apolipoproteins)
0 (Apolipoproteins B)
0 (Cholesterol, HDL)
0 (Cholesterol, LDL)
تواريخ الأحداث: Date Created: 20140702 Date Completed: 20150221 Latest Revision: 20211021
رمز التحديث: 20231215
مُعرف محوري في PubMed: PMC4058853
DOI: 10.1155/2014/709756
PMID: 24982904
قاعدة البيانات: MEDLINE
الوصف
تدمد:2314-6141
DOI:10.1155/2014/709756