دورية أكاديمية

Performance of osteopontin in the diagnosis of malignant pleural mesothelioma: a meta-analysis.

التفاصيل البيبلوغرافية
العنوان: Performance of osteopontin in the diagnosis of malignant pleural mesothelioma: a meta-analysis.
المؤلفون: Lin H; Department of Rheumatology and Immunology, West China Hospital of Sichuan University Chengdu, China., Shen YC; Department of Pulmonary Diseases, State Key Laboratory of Biotherapy of China and Department of Respiratory Medicine, West China Hospital of Sichuan University Chengdu, China., Long HY; Department of Pulmonary Diseases, State Key Laboratory of Biotherapy of China and Department of Respiratory Medicine, West China Hospital of Sichuan University Chengdu, China., Wang H; Department of Pulmonary Diseases, State Key Laboratory of Biotherapy of China and Department of Respiratory Medicine, West China Hospital of Sichuan University Chengdu, China., Luo ZY; West China School of Medicine, Sichuan University Chengdu, China., Wei ZX; West China School of Medicine, Sichuan University Chengdu, China., Hu SQ; West China School of Medicine, Sichuan University Chengdu, China., Wen FQ; Department of Pulmonary Diseases, State Key Laboratory of Biotherapy of China and Department of Respiratory Medicine, West China Hospital of Sichuan University Chengdu, China.
المصدر: International journal of clinical and experimental medicine [Int J Clin Exp Med] 2014 May 15; Vol. 7 (5), pp. 1289-96. Date of Electronic Publication: 2014 May 15 (Print Publication: 2014).
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: e-Century Pub. Corp Country of Publication: United States NLM ID: 101471010 Publication Model: eCollection Cited Medium: Print ISSN: 1940-5901 (Print) Linking ISSN: 19405901 NLM ISO Abbreviation: Int J Clin Exp Med Subsets: PubMed not MEDLINE
أسماء مطبوعة: Original Publication: Madison, WI : e-Century Pub. Corp.
مستخلص: It is reported that osteopontin has shown promising diagnostic value for malignant pleural mesothelioma (MPM), this meta-analysis aimed to establish the overall diagnostic accuracy of the osteopontin measurement for diagnosing MPM. Based on a systematic review of English language studies, the sensitivity, specificity and other measures of accuracy of osteopontin in the diagnosis of MPM were pooled using random-effects model. Summary receiver operating characteristic curves were used to summarize overall test performance. Seven publications met our inclusion criteria, the pooled sensitivity was 0.57 (95%CI: 0.52-0.61), specificity was 0.81, 95%CI: 0.79-0.84). The PLR was 3.78 (95%CI: 2.23-6.41), the NLR was 0.51 (95%CI: 0.38-0.67) and the DOR was 9.04 (95%CI: 5.28-15.48), the area under the summary receiver operating characteristic curve was 0.80. Our data suggest that osteopontin is likely to be a useful diagnostic marker for MPM, considering for the limited studies and patients included, larger studies are needed to confirm these findings.
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فهرسة مساهمة: Keywords: Osteopontin; malignant pleural mesothelioma; meta-analysis
تواريخ الأحداث: Date Created: 20140705 Date Completed: 20140704 Latest Revision: 20211021
رمز التحديث: 20221213
مُعرف محوري في PubMed: PMC4073746
PMID: 24995085
قاعدة البيانات: MEDLINE