دورية أكاديمية
أعرض في EDS

Hematological and biochemical markers of iron status in a male, young, physically active population.

التفاصيل البيبلوغرافية
العنوان: Hematological and biochemical markers of iron status in a male, young, physically active population.
المؤلفون: Nunes LA; Faculty of Biomedical Sciences, Metrocamp College-IBMEC Group, 13035-270 Campinas, SP, Brazil., Grotto HZ; Department of Clinical Pathology, School of Medical Sciences, State University of Campinas, 13083-881 Campinas, SP, Brazil., Brenzikofer R; Laboratory of Instrumentation for Biomechanics, Physical Education Institute, State University of Campinas, 13083-851 Campinas, SP, Brazil., Macedo DV; Laboratory of Exercise Biochemistry-LABEX, Biochemistry Department, Biology Institute, State University of Campinas, 13083-970 Campinas, SP, Brazil.
المصدر: BioMed research international [Biomed Res Int] 2014; Vol. 2014, pp. 349182. Date of Electronic Publication: 2014 Jun 22.
نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't
اللغة: English
بيانات الدورية: Publisher: Hindawi Pub. Co Country of Publication: United States NLM ID: 101600173 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2314-6141 (Electronic) NLM ISO Abbreviation: Biomed Res Int Subsets: MEDLINE
أسماء مطبوعة: Original Publication: New York, NY : Hindawi Pub. Co.
مواضيع طبية MeSH: Exercise*, Biomarkers/*blood , C-Reactive Protein/*metabolism , Iron/*metabolism, Adult ; Ferritins/blood ; Hematologic Tests ; Humans ; Japan ; Leukocyte Count ; Male ; Reference Values ; Transferrins/blood
مستخلص: The aim of this study was to establish reference intervals (RIs) for the hemogram and iron status biomarkers in a physically active population. The study population included male volunteers (n = 150) with an average age of 19 ± 1 years who had participated in a regular and controlled exercise program for four months. Blood samples were collected to determine hematological parameters using a Sysmex XE-5000 analyzer (Sysmex, Kobe, Japan). Iron, total iron-binding capacity (TIBC), transferrin saturation and ferritin, and high-sensitivity C-reactive protein (CRP) concentrations in serum samples were measured using commercial kits (Roche Diagnostics, GmbH, Mannheim, Germany) and a Roche/Hitachi 902 analyzer. The RIs were established using the RefVal program 4.1b. The leucocyte count, TIBC, and CRP and ferritin concentrations exhibited higher RIs compared with those in a nonphysically active population. Thirty volunteers (outliers) were removed from the reference population due to blood abnormalities. Among the outliers, 46% exhibited higher CRP concentrations and lower concentrations of iron and reticulocyte hemoglobin compared with the nonphysically active population (P < 0.001). Our results showed that it is important to establish RIs for certain laboratory parameters in a physically active population, especially for tests related to the inflammatory response and iron metabolism.
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المشرفين على المادة: 0 (Biomarkers)
0 (Transferrins)
9007-41-4 (C-Reactive Protein)
9007-73-2 (Ferritins)
E1UOL152H7 (Iron)
تواريخ الأحداث: Date Created: 20140722 Date Completed: 20150312 Latest Revision: 20220318
رمز التحديث: 20221213
مُعرف محوري في PubMed: PMC4090577
DOI: 10.1155/2014/349182
PMID: 25045665
قاعدة البيانات: MEDLINE
الوصف
تدمد:2314-6141
DOI:10.1155/2014/349182