دورية أكاديمية
Do thrombotic events during endovascular interventions lead to poorer outcomes in patients with severe limb ischemia?
| العنوان: | Do thrombotic events during endovascular interventions lead to poorer outcomes in patients with severe limb ischemia? |
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| المؤلفون: | Chia D; Ministry of Health Holdings, Singapore., May KK; Department of Cardiothoracic and Vascular Surgery, National University Health System, Singapore., Zaw MH; Department of Surgery, National University of Singapore, Singapore., Hartman M; Department of Surgery, National University of Singapore, Singapore., Robless PA; Department of Cardiothoracic and Vascular Surgery, National University Health System, Singapore., Ho P; Department of Cardiothoracic and Vascular Surgery, National University Health System, Singapore surhp@nus.edu.sg. |
| المصدر: | Vascular [Vascular] 2015 Jun; Vol. 23 (3), pp. 245-52. Date of Electronic Publication: 2014 Aug 19. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Sage Country of Publication: England NLM ID: 101196722 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1708-539X (Electronic) Linking ISSN: 17085381 NLM ISO Abbreviation: Vascular Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: Dec. 2012- : London : Sage Original Publication: Hamilton, Ont., Canada : BC Decker, [2004]- |
| مواضيع طبية MeSH: | Amputation, Surgical/*adverse effects , Endovascular Procedures/*adverse effects , Ischemia/*surgery , Limb Salvage/*adverse effects , Thrombosis/*etiology, Adult ; Aged ; Aged, 80 and over ; Female ; Humans ; Lower Extremity/blood supply ; Male ; Middle Aged ; Risk Assessment ; Treatment Outcome |
| مستخلص: | Introduction: Intra-procedural acute thrombosis (IPAT) is a complication of endovascular procedures. We aim to identify risk factors for IPAT and compare the outcomes of patients with or without IPAT. Methods: Paired T test and χ (2) test were used to identify risk factors and short-term outcomes. Kaplan-Meier survival analysis was used for mid-term outcomes. Results: A total of 228 procedures were performed with 21 IPAT events (9.21%). The odds ratio of Indian patients developing IPAT was 2.8x (95% CI 1.1-7.6). Patients with in-stent occlusion or prior IPAT were 5.6x (95% CI 1.3-24.2) and 5.6x (95% CI 1.3-24.4) more likely to develop an IPAT event. Patients without IPAT had significantly more improvement in mean runoff score (-1.15 ± 1.31, p < 0.01). The odds of patients with IPAT requiring subsequent endovascular intervention and arterial bypass surgery were 4.2x (95% CI 1.6-10.7) and 7.1x (95% CI 1.9-27.0). There was no significant Kaplan-Meier estimated overall survival or amputation-free survival difference between patients with or without IPAT event. Conclusion: Indian ethnicity, in-stent occlusion and previous IPAT were associated with higher risk of IPAT. Even after successful endovascular salvage, patients with IPATs were more likely to require secondary revascularization procedure. Patients with IPATs had no decrease in overall survival or amputation-free survival. (© The Author(s) 2014 Reprints and permissions: sagepub.co.uk/journalsPermissions.nav.) |
| فهرسة مساهمة: | Keywords: Acute thrombosis; distal embolization; endovascular intervention; peripheral vascular disease |
| تواريخ الأحداث: | Date Created: 20140821 Date Completed: 20160823 Latest Revision: 20221207 |
| رمز التحديث: | 20231215 |
| DOI: | 10.1177/1708538114546367 |
| PMID: | 25139593 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 1708-539X |
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| DOI: | 10.1177/1708538114546367 |