دورية أكاديمية
أعرض في EDS

Thalassophryne nattereri fish venom: from the envenoming to the understanding of the immune system.

التفاصيل البيبلوغرافية
العنوان: Thalassophryne nattereri fish venom: from the envenoming to the understanding of the immune system.
المؤلفون: Lopes-Ferreira M; Unidade de Imunorregulação, Laboratório Especial de Toxinologia Aplicada (CEPID/FAPESP), Instituto Butantan, Av. Vital Brazil, 1500 São Paulo, SP, CEP 05503-900, Brasil., Grund LZ; Unidade de Imunorregulação, Laboratório Especial de Toxinologia Aplicada (CEPID/FAPESP), Instituto Butantan, Av. Vital Brazil, 1500 São Paulo, SP, CEP 05503-900, Brasil., Lima C; Unidade de Imunorregulação, Laboratório Especial de Toxinologia Aplicada (CEPID/FAPESP), Instituto Butantan, Av. Vital Brazil, 1500 São Paulo, SP, CEP 05503-900, Brasil.
المصدر: The journal of venomous animals and toxins including tropical diseases [J Venom Anim Toxins Incl Trop Dis] 2014 Aug 13; Vol. 20, pp. 35. Date of Electronic Publication: 2014 Aug 13 (Print Publication: 2014).
نوع المنشور: Journal Article; Review
اللغة: English
بيانات الدورية: Publisher: CEVAP Country of Publication: Brazil NLM ID: 101201501 Publication Model: eCollection Cited Medium: Print ISSN: 1678-9199 (Print) Linking ISSN: 16789180 NLM ISO Abbreviation: J Venom Anim Toxins Incl Trop Dis Subsets: PubMed not MEDLINE
أسماء مطبوعة: Publication: 2019- : Botucatu, SP, Brazil : CEVAP
Original Publication: Botucatu, SP, Brazil : CEVAP, c2003-
مستخلص: Thalassophryne nattereri (niquim) is a venomous fish found off North and Northeast coast of Brazil, where it is known by the severity of the accidents involving humans. This review article is divided into four topics. The first one provides a brief description of the animal biology and its distribution off Brazilian coastal waters, the venom apparatus, signs and symptoms observed in envenomated humans and also describes envenomation in mice. The second topic describes the use of modern genetic approach and mass spectrometry for identification of highly expressed genes in its venom glands and the sequence of major toxins. The third chapter offers a detailed study of tissue injury induced by the venom and reveals the role of toxins that impair inflammation reduction. Finally, the fourth section expands the understanding of many extrinsic and intrinsic essential factors in maintaining survival of memory B cell compartment. Our results demonstrate the wide possibilities for research in the area of toxinology, also the necessity of interconnection among biochemistry, pharmacology and immunology areas for the expansion of knowledge and for generation of innovation.
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فهرسة مساهمة: Keywords: Immunological memory; Nattectin; Natterin; Thalassophryne nattereri; Venomous fish
تواريخ الأحداث: Date Created: 20140821 Date Completed: 20140820 Latest Revision: 20211021
رمز التحديث: 20240628
مُعرف محوري في PubMed: PMC4137268
DOI: 10.1186/1678-9199-20-35
PMID: 25140174
قاعدة البيانات: MEDLINE
الوصف
تدمد:1678-9199
DOI:10.1186/1678-9199-20-35