دورية أكاديمية
A current understanding of vascular calcification in CKD.
| العنوان: | A current understanding of vascular calcification in CKD. |
|---|---|
| المؤلفون: | Paloian NJ; Division of Nephrology, Department of Pediatrics, University of Washington School of Medicine, Seattle, Washington; and., Giachelli CM; Department of Bioengineering, University of Washington, Seattle, Washington ceci@uw.edu. |
| المصدر: | American journal of physiology. Renal physiology [Am J Physiol Renal Physiol] 2014 Oct 15; Vol. 307 (8), pp. F891-900. Date of Electronic Publication: 2014 Aug 20. |
| نوع المنشور: | Journal Article; Review |
| اللغة: | English |
| بيانات الدورية: | Publisher: American Physiological Society Country of Publication: United States NLM ID: 100901990 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1522-1466 (Electronic) Linking ISSN: 15221466 NLM ISO Abbreviation: Am J Physiol Renal Physiol Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: Bethesda, Md. : American Physiological Society, c1997- |
| مواضيع طبية MeSH: | Kidney Failure, Chronic/*physiopathology , Renal Insufficiency, Chronic/*physiopathology , Vascular Calcification/*physiopathology, Calcium/metabolism ; Disease Progression ; Elastin/metabolism ; Humans ; Muscle, Smooth, Vascular/cytology ; Phosphorus/metabolism ; Risk Factors ; Vascular Calcification/pathology |
| مستخلص: | Patients with chronic kidney disease (CKD) and end-stage renal disease (ESRD) have significant cardiovascular morbidity and mortality that is in part due to the development of vascular calcification. Vascular calcification is an active, highly regulated process that shares many similarities with normal bone formation. New discoveries related to extracellular vesicles, microRNAs, and calciprotein particles continue to reveal the mechanisms that are involved in the initiation and progression of vascular calcification in CKD. Further innovations in these fields are critical for the development of biomarkers and therapeutic options for patients with CKD and ESRD. (Copyright © 2014 the American Physiological Society.) |
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| معلومات مُعتمدة: | R01 HL062329 United States HL NHLBI NIH HHS; R01 HL114611 United States HL NHLBI NIH HHS; T32 DK007662 United States DK NIDDK NIH HHS; R01 HL081785 United States HL NHLBI NIH HHS; P30 DK017047 United States DK NIDDK NIH HHS |
| فهرسة مساهمة: | Keywords: calciprotein particles; chronic kidney disease; microRNA; vascular calcification; vesicles |
| المشرفين على المادة: | 27YLU75U4W (Phosphorus) 9007-58-3 (Elastin) SY7Q814VUP (Calcium) |
| تواريخ الأحداث: | Date Created: 20140822 Date Completed: 20150303 Latest Revision: 20220310 |
| رمز التحديث: | 20231215 |
| مُعرف محوري في PubMed: | PMC4200295 |
| DOI: | 10.1152/ajprenal.00163.2014 |
| PMID: | 25143458 |
| قاعدة البيانات: | MEDLINE |
| تدمد: | 1522-1466 |
|---|---|
| DOI: | 10.1152/ajprenal.00163.2014 |