دورية أكاديمية
أعرض في EDS

Reproducibility of retinal oxygen saturation in normal and treated glaucomatous eyes.

التفاصيل البيبلوغرافية
العنوان: Reproducibility of retinal oxygen saturation in normal and treated glaucomatous eyes.
المؤلفون: Goharian I; Department of Ophthalmology, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Palm Beach Gardens, Florida, USA., Iverson SM; Department of Ophthalmology, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Palm Beach Gardens, Florida, USA., Ruiz RC; Department of Ophthalmology, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Palm Beach Gardens, Florida, USA., Kishor K; Department of Ophthalmology, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Palm Beach Gardens, Florida, USA., Greenfield DS; Department of Ophthalmology, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Palm Beach Gardens, Florida, USA., Sehi M; Department of Ophthalmology, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Palm Beach Gardens, Florida, USA.
المصدر: The British journal of ophthalmology [Br J Ophthalmol] 2015 Mar; Vol. 99 (3), pp. 318-22. Date of Electronic Publication: 2014 Sep 24.
نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
اللغة: English
بيانات الدورية: Publisher: BMJ Pub. Group Country of Publication: England NLM ID: 0421041 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1468-2079 (Electronic) Linking ISSN: 00071161 NLM ISO Abbreviation: Br J Ophthalmol Subsets: MEDLINE
أسماء مطبوعة: Publication: Jan. 1992- : London : BMJ Pub. Group
Original Publication: 1917-Dec. 1991: London : British Medical Association
مواضيع طبية MeSH: Glaucoma/*physiopathology , Oxygen/*blood , Retinal Vessels/*physiopathology, Adult ; Aged ; Antihypertensive Agents/therapeutic use ; Female ; Glaucoma/drug therapy ; Humans ; Intraocular Pressure/physiology ; Male ; Middle Aged ; Oximetry ; Oxygen Consumption ; Prospective Studies ; Regional Blood Flow ; Reproducibility of Results ; Tonometry, Ocular
مستخلص: Aim: To measure the reproducibility of retinal oxygen saturation (SaO2) levels among treated glaucomatous eyes and normal controls in a prospective non-randomised study.
Methods: Patients with perimetric glaucoma (PG) and normal controls were included. Exclusion criteria for both groups included visual acuity <20/30, unreliable visual fields, thyroidopathies, hemoglobinopathies, cardiovascular and pulmonary diseases. Retinal oximetry was performed twice consecutively on one randomly selected eye of PG and normal controls using spectrophotometric retinal oximeter (SRO; Oxymap ehf., Iceland). Four main retinal vessel pairs were analysed separately. Coefficients of variability (CoV), coefficients of repeatability (CoR) and intraclass correlation coefficients (ICCs) in arteries (a.SaO2) and veins (v.SaO2) were calculated.
Results: 23 PG (mean age 68.3±10.8 years) and 22 normal subjects (mean age 61.5±18.2 years; p=0.14) were included. The intraocular pressure and mean ocular perfusion pressure in glaucoma (14.4±4.2 mm Hg; 45.8±5.8 mm Hg) and controls (14.3±3.3 mm Hg; 45.8±6.1 mm Hg) were similar (p >0.05). In the PG group, the a.SaO2 had a CoV of 1.6%, a CoR of 4.7 and an ICC of 0.97; the v.SaO2 had a CoV of 5.9%, a CoR of 8.7 and an ICC of 0.96. In normals, the a.SaO2 had a CoV of 0.98%, a CoR of 3.3 and an ICC of 0.97; the v.SaO2 had a CoV of 4.8%, a CoR of 7.7 and an ICC of 0.93.
Conclusions: Retinal oximetry measurements using SRO are highly reproducible in both treated glaucomatous and normal eyes.
(Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.)
معلومات مُعتمدة: P30EY014801 United States EY NEI NIH HHS
فهرسة مساهمة: Keywords: Glaucoma
المشرفين على المادة: 0 (Antihypertensive Agents)
S88TT14065 (Oxygen)
تواريخ الأحداث: Date Created: 20140926 Date Completed: 20150521 Latest Revision: 20220321
رمز التحديث: 20231215
DOI: 10.1136/bjophthalmol-2014-305718
PMID: 25253765
قاعدة البيانات: MEDLINE
الوصف
تدمد:1468-2079
DOI:10.1136/bjophthalmol-2014-305718