دورية أكاديمية
Effect of delta sleep-inducing peptide on the expression of antioxidant enzyme genes in the brain and blood of rats during physiological aging.
| العنوان: | Effect of delta sleep-inducing peptide on the expression of antioxidant enzyme genes in the brain and blood of rats during physiological aging. |
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| المؤلفون: | Kutilin DS; South Federal University, Rostov-on-Don, Russia., Bondarenko TI, Kornienko IV, Mikhaleva II |
| المصدر: | Bulletin of experimental biology and medicine [Bull Exp Biol Med] 2014 Sep; Vol. 157 (5), pp. 616-9. Date of Electronic Publication: 2014 Sep 26. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Springer Country of Publication: United States NLM ID: 0372557 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1573-8221 (Electronic) Linking ISSN: 00074888 NLM ISO Abbreviation: Bull Exp Biol Med Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: New York : Springer Original Publication: New York, Consultants Bureau. |
| مواضيع طبية MeSH: | Aging/*metabolism , Antioxidants/*metabolism , Brain/*enzymology , Delta Sleep-Inducing Peptide/*pharmacology , Glutathione Peroxidase/*metabolism , Superoxide Dismutase/*metabolism, Aging/blood ; Animals ; Delta Sleep-Inducing Peptide/administration & dosage ; Glutathione Peroxidase/blood ; Injections, Subcutaneous ; Male ; Rats ; Rats, Wistar ; Superoxide Dismutase/blood |
| مستخلص: | Subcutaneous injections of exogenous delta sleep-inducing peptide in a dose of 100 μg/kg (monthly, 5-day courses) to rats of various age groups (2-24 months) were followed by an increase in the expression of genes for SOD 1 (Sod1) and glutathione peroxidase 1 (Gpx1) in the brain and nucleated blood cells. The expression of these genes was shown to decrease during physiological aging of the body. |
| المشرفين على المادة: | 0 (Antioxidants) 69431-45-4 (Delta Sleep-Inducing Peptide) EC 1.11.1.9 (Glutathione Peroxidase) EC 1.15.1.1 (Superoxide Dismutase) |
| تواريخ الأحداث: | Date Created: 20140927 Date Completed: 20150608 Latest Revision: 20141002 |
| رمز التحديث: | 20231215 |
| DOI: | 10.1007/s10517-014-2628-4 |
| PMID: | 25257425 |
| قاعدة البيانات: | MEDLINE |
Find this article in full text from Springer Verlag. 
Full Text Finder | تدمد: | 1573-8221 |
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| DOI: | 10.1007/s10517-014-2628-4 |